Retina

Serum and aqueous levels of Klotho levels are reduced in pseudoexfoliation syndrome (PXF) and pseudoexfoliative glaucoma (PEG) while Endothelin-1 (ET-1) is increased, researchers say.

Looking back at 2016, incremental improvements in devices are changing how retina surgeons approach and treat surgeries, said a group of experts. For Charles Wykoff, MD, PhD, two novel improvements may not radically alter surgical approaches today, but will have a long-lasting impact down the road.

Millions of adults around the world run the risk of losing their eyesight because of inattention to complications of diabetes, according to a team of international researchers. “A quarter of people with diabetes surveyed are not discussing eye complications with their health care professional, with many presenting when vision problems have already occurred,” the report said.

Optical services chains in the United Kingdom are misleading customers about filters to screen out blue light from electronic devices, according to the BBC. Boots Opticians and Vision Express both claim that the filters protect against retinal damage despite a lack of evidence, the news service said in a recent press release.

The Mediterranean diet reduces the risk of age-related macular degeneration (AMD), according to a study of two Portuguese populations.

Accumulating evidence suggests that multiple treatments can help people with amblyopia, according to a review of the literature.

The US Food and Drug Administration (FDA) is expediting its review of a new potential treatment for giant cell arteritis, a rare inflammatory disease that can cause permanent vision loss, Roche has announced.

Work is progressing on contact lenses that can monitor biomarkers in tear film for intraocular pressure, diabetes mellitus, and other health conditions.

Patients treated for diabetic macular oedema with ranibizumab in the UK National Health Service (NHS) are getting benefits similar to those seen in clinical trials, according to a new study

A 6-month analysis from the REINFORCE study of the dexamethasone intravitreal implant Ozurdex found an average of one- to two-line vision gains and no new safety concerns.

Screening programmes could catch diabetic retinopathy in children earlier if they began screening 6 years after diabetes is diagnosed.

Sabin Dang, MD, didn’t have as clear cut of a journey to the ophthalmic world as many would expect. While today he spends his working hours improving visual outcomes of patients at Ophthalmic Consultants of Boston, a few years ago you would have found him creating coding software in his IT consulting company to help businesses grow.

Studies in mice suggest that a technology based on topical endoscope fundus imaging could allow early diagnosis of Alzheimer’s disease, researchers have said.

Experience with en face OCT shows its value for following disease progression in wet and dry age-related macular degeneration and in diseases that disrupt the inner segment/outer segment/ellipsoid zone.

Surgeons may safely delay operating on rhegmatogenous retinal detachment (RRD) for a few days to accommodate their schedules, a new study suggested.

The Novel Evidenced Assessment of Tortuosity (NEAT) system is intuitive and works even with poor images, according to its creators, Konstantinos Balaskas and his colleagues at Manchester Royal Eye Hospital and five other centres in the United Kingdom.

Retina surgeons considered 2015 to be an exciting time in the subspecialty in all areas and pointed to the availability and increased use of 27-gauge instrumentation as one of the real highlights of surgical retina.

Analysis of eyes with and without prior vitrectomy from DRCR Protocol I showed similar results when treated with ranibizumab with prompt or deferred laser.

In a 1-year comparison of intravitreous aflibercept, bevacizumab and ranibizumab therapy for centre-involved DME, aflibercept was more effective at improving vision among patients who started treatment at lower levels of visual acuity.

Researchers using the AREDS lens grading scale have found that long-term clinically relevant outcomes can be predicted by 2-year changes in severity of lens opacities.

NICE has released a draft decision recognizing the benefits of aflibercept solution for injection for the majority of patients with visual impairment caused by DME.

Patients who receive triamcinolone acetonide treatment for DME demonstrate changes in OCT reflectivity in their foveal cystoid spaces that are associated with a rebound in macular thickening and visual deterioration.

The posterior retina is a site of oxytocin (OXT) activation of the oxytocin receptor (OXTR), according to a study published online.

The NHS is facing issues related to the diagnosing, treating and managing the growing number of ageing people affected by AMD, the leading cause of blindness in the Western world.

A proprietary retinal laser technology has demonstrated the potential to reverse the accumulation of drusen in patients with high-risk early AMD over a 24-month period.