Pediatrics

VG801 is a dual AAV gene therapy that leverages mRNA trans-splicing via the vgRNA REVeRT and vgAAV platforms to deliver the full-length ABCA4 gene for Stargardt disease and related retinal disorders.

IVMED-85 is a preservative-free, non-atropine daily drop that slows myopia progression by strengthening scleral and corneal collagen crosslinks via LOX activation.

The investigators described the CASIA2 (Tomey Corporation) instrument, which is a new AS-OCT device with a swept-source laser wavelength of 1,310 nm that can scan at a speed of 50,000 A-scan/second.

ABCA4-associated retinopathies include Stargardt disease, retinitis pigmentosa 19, and cone-rod dystrophy 3.

Machine learning algorithms enhance retinopathy of prematurity screening using smartphone images, expanding access in low-resource settings and easing pediatric ophthalmologist workloads.

The clearance expands its existing label from patients aged 4 to 7 years to patients aged 4 to under 13 years.

Chinese researchers reveal that low-level red light therapy may control myopia in children but raises concerns about retinal damage and cone density reduction.

ENTOD Pharmaceuticals launches Myatro XL, a 0.05% atropine eye drop, to effectively slow myopia progression in children, available by prescription in 2025.

This population requires careful attention from diagnosis through the entire postoperative process.

The affected mandate requires that all newborns receive erythromycin ointment applied to their eyes after birth, which helps prevent ophthalmia neonatorum.

The new data builds upon previously reported 6- and 12-month positive results from adult patients treated in the same study.

A study found that children with early-onset atopic dermatitis have a higher risk of developing uveitis and should be closely monitored for its onset.

Accelerated changes in the spherical equivalent refraction (SER) and axial length were seen but no changes in the lens power and thickness were seen in pediatric patients.

The study findings indicated that lifestyle changes associated with the COVID-19 pandemic were connected to an increase in childhood astigmatisms.

The award honors Ludwig von Sallmann, MD, a “distinguished international ophthalmologist and ophthalmic investigator whose contributions greatly increased the basic and clinical understanding of vision and ophthalmology.”

The FDA has set a PDUFA target action date of October 23, 2025, for the low-dose atropine formulation.

Inflammation and scarring are the primary obstacles with pirfenidone.

These tools help fill a gap that current technologies cannot achieve as effectively.

Children experienced sudden vision loss, visual field constriction, nyctalopia and dyschromatopsia following febrile illness.

The research team conducted a prospective study to assess any barriers to parental compliance with vision testing in preschoolers aged 3 to 6 years.

Zhaoke Ophthalmology Limited is responsible for developing and obtaining regulatory approval for NVK-002 in Greater China, South Korea, and the Southeast Asian territories.

Cost among other factors may deter patients from screening, especially in rural and low-resource settings.

The rationale was that commercial mydriatics administered during retinopathy of prematurity (ROP) screening have been associated with cardiorespiratory and gastrointestinal adverse events.

Researchers at the University of Colorado Anschutz Medical Campus found that characters with crossed or drifting eyes are more likely to play more minor roles in animated movies and be considered unintelligent or villainous. These depictions, the researchers say, can have harmful effects for children with strabismus by perpetuating stereotypes.

In the wake of a report by a group of researchers in China detailing the increasing prevalence of myopia worldwide, Daniel Cyr, MD, a pediatric ophthalmologist at Stony Brook Medicine, agreed with its assessment, telling Ophthalmology Times he is seeing an increase in pediatric myopia at his clinic in New York.

Research is needed to establish the best diagnostic and management strategies for increasingly common condition

The designations underscore the unmet need in Stargardt disease, a rare and serious pediatric disease for which no treatment exists.

NEI Initiative aims to boost awareness, standardize diagnosis, and improve care for children with CVI through multidisciplinary collaboration and emerging technologies.