Investigators explore pathogenic cytokines as biomarkers for DME
January 14, 2021
BIGH3 is an extracellular matrix protein that can act in an autocrine, paracrine manner.
© 2021 MJH Life Sciences™ and Ophthalmology Times. All rights reserved.
Gene Therapy
Leber hereditary optic neuropathy: Outlining disease’s natural course
January 15, 2021
A new gene therapy for this patient population targets the ND4 gene mutation.
Gyroscope Therapeutics, UPenn to develop gene therapies for serious eye diseases
January 10, 2021
Two teams of researchers from Gyroscope Therapeutics and the University of Pennsylvania are joining forces to explore gene therapy targets for three specific serious eye diseases.
Patient enrollment completed for Phase 2/3 Illuminate study of candidate for treatment of LCA10
January 07, 2021
The investigational RNA therapy is designed to address the underlying cause of Leber congenital amaurosis 10 due to a mutation in the CEP290 gene.
Collaboration formed to develop AAV-based gene therapies for eye disease
January 06, 2021
ViGeneron and Biogen this week have announced a global collaboration and licensing agreement in which the partners will develop and commercialize gene therapy products based on adeno-associated virus (AAV) vectors that treat inherited eye disease.
Gene therapy surgical pearls for successful outcomes
January 04, 2021
Nine pediatric patients with Leber congenital amaurosis show visual improvement in clinical trials.
Ocular gene therapy offers hope for inherited retinal disease
December 17, 2020
With several clinical trials underway, ocular therapy is seen as having potential in the treatment of a number of gene-related diseases.
Study: Some RP abnormalities are linked with lower visual acuity
December 02, 2020
Patients with pathogenic variants experience lower VA tied to length of IS/OS junction.
Gene panel offers expanded diagnostic capability of inherited retinal diseases
November 24, 2020
Investigators reviewed visual acuity, multi-modal retinal imaging, electroretinography, family history.
Internet hawkers of stem cell therapies raising red flags
November 20, 2020