Trevor Lamb, ScD, FRS, FAA, of the John Curtin School of MedicalResearch, Australian National University, Canberra, Australia, andEdward Pugh Jr., PhD, from the F.M. Kirby Center for MolecularOphthalmology, Scheie Eye Institute, University of Pennsylvania,Philadelphia, share the 2006 Proctor Medal and Lecture for thedevelopment of a comprehensive model of photoexcitation in rodreceptors and its application to the electroretinogram (ERG). Thiswork led to the use of the ERG in the analysis of deficits in avariety of basic and clinical situations.