Cornea

Shifting the treatment paradigm can lead to less pain and inflammation.

The funding has been awarded to BIENCO, which is working to cure one of the most common causes of blindness in the world by developing cost effective, individually tailored, superior corneas.

OK-101 is the first IND clearance granted by the FDA for a drug to begin clinical studies specifically to treat patients suffering with neuropathic corneal pain.

Patient selection is important.

Researchers found the administration of the neuropeptide α–melanocyte–stimulating hormone promotes corneal healing and restores normal eye function to an otherwise degenerating and diseased cornea by providing protection against cell death and promoting cell regeneration.

Physicians from the Harvard Medical School and the Kresge Eye Institute at Wayne State University in Detroit recently published details from the case.

Approach to lowering IOP reduces medication burden without risking graft rejection.

Sterile corneal ulceration is a rare complication of rheumatoid arthritis and may lead to corneal perforation. However, surgeries performed to restore vision often are not successful.

Physician notes endothelial cells play key role in hydration, transparency of cornea.

Acanthamoeba keratitis can lead to inflammation of the cornea and result in extreme levels of pain, light sensitivity and vision loss.

The ANTERION from Heidelberg Engineering offers a range of advanced diagnostic tools, including IOL power calculation, corneal topography, and tomography.

Held the second Thursday each October, World Sight Day is an annual day of awareness to focus global attention on blindness and vision impairment.

The team focused on the research pf the senescent phenotypes of human corneal and conjunctival epithelial cells.

According to the company, study enrollment is planned to commence during Q1 2024 following IND allowance by the FDA.

Steven A. Greenstein, MD, emphasizes the importance of identifying and assessing eye emergencies, highlighting the need to determine when to escalate care from primary to subspecialty settings. He discusses various types of anterior segment emergencies, while stressing the significance of maintaining a calm demeanor in these critical situations.

A rapid lateral-flow device shows high sensitivity and specificity in identifying Aspergillus species in corneal samples, aiding in diagnosing microbial keratitis. The device, coupled with ratiometric analysis, proves robust and cost-effective, potentially revolutionizing MK diagnosis, especially in low-resource settings

Noncontact esthesiometry screens for all levels of neurotrophic keratitis.

The study of pathological tissues will enable to establish the role of corneal structure in certain diseases.

The trial will be conducted by French tissue bank, TBF Génie Tissulaire.

Treating the meibomian glands and lifestyle changes are among some of the treatment methods.

Henriquez pointed out that waiting for keratoconic progression runs the inherent risk that keratoconus will progress rapidly and affect the planned initial treatment protocol.

Cultivated autologous limbal epithelial cells (CALEC) procedure shown to be safe and feasible with early positive results of restored cornea surfaces or vision gains in four patients with severe chemical burns.

According to the company, the primary endpoint for the NEXPEDE-1 study of lufepirsen ophthalmic gel will be complete corneal healing as determined by corneal fluorescein staining.

An area that attracts tourists and Christian pilgrims from around the world, has been found to contain microsporidium, which can cause corneal infections.

The trial will be an open-label trial in partnership with Tufts Medical Center. OK-101 is also being developed for use in dry eye disease.

This NDA transfer marks the fourth FDA-approved ophthalmic product purchased by Harrow earlier in 2023 now commercially available in the US.

With the potential to impact millions of patients, a study finds that biomimetic materials pulsed with low-energy blue light can reshape damaged corneas, including thickening the tissue.

Cedars-Sinai research is the first to uncover disease-related changes to the cornea and to propose potential therapeutic approaches to correct diabetic wound healing.

A recent study demonstrates the safety and efficacy of treating eyes with cross-linking after keratoconus relapses following keratoplasty.