News

A new product (NutriDox Convenience Kit, Advanced Vision Research) is designed to make the treatment of meibomitis, posterior blepharitis, and meibomian gland disease more convenient for patients and clinicians. The prescription-only system includes an antibiotic, nutrition therapy, and a lid-cleansing component.

A novel ophthalmic anti-allergy agent, epinastine HCl ophthalmic solution 0.05% (Elestat, Inspire Pharmaceuticals), effectively controls ocular allergy in patients with dry eye, according to Jodi Luchs, MD, FACS. The drop has been shown to rapidly prevent ocular allergy symptoms by blocking H1 and H2 receptors, stabilizing mast cells, and inhibiting the release of proinflammatory mediators.

Important differences exist between the various classes of over-the-counter eye drops. Physicians play a vital role in explaining these differences, as well as their potential implications in the treatment of the symptoms of dry eye and other conditions, to patients. Educating patients about the available formulations not only may expedite the relief of their symptoms but also may save them time and money.

Everyone is given a special talent, which, if developed, can allow them to perform their talent really well. This explains why there are great singers, superb artists or musicians, and gifted mechanics, to name a few professions. Those talents often are limited to that particular setting, however; they are not always transferable into another area.

To help combat the unfavorable view the public has about pharmaceutical companies, the Pharmaceutical Research and Manufacturers of America (PhRMA) recently published updates to their "Code on Interactions with Health-care Professionals," which went into effect Jan. 1. PhRMA's basis for the updates is that "interactions should be focused on informing health-care professionals about products, providing scientific and educational information, and supporting medical education." Changes have been made in three major categories: gifting, consulting, and enforcement of the code.

The World Glaucoma Association and the World Glaucoma Patient Association have set March 12 as the second annual World Glaucoma Day.

Patients treated with ecabet sodium demonstrated a strong positive trend in the objective sign of tear film break-up time and a positive trend in the objective sign of quantity of tears produced in a phase IIb study conducted by ISTA Pharmaceuticals.

Pfizer will acquire Wyeth in a cash-and-stock transaction valued at $50.19 per share, or a total of about $68 billion, as of the Jan. 26 announcement of the planned merger.

This is the time of year that my administrator asks me: "So, where are we going in the new year? What I have finally come to learn is that instead of asking, "Where are we going?" it is more valuable to ask, "Where have we been?"

In a small pilot study with limited follow-up, early application of micropulse laser trabeculoplasty (MLT) using a specific diode laser (IQ810, Iridex Corp.) appeared promising. Use of this multifunctional laser may have practical advantages in a clinical setting. Further study of the technology is needed to determine the role of MLT in the treatment of glaucoma.

JPE1375 (Jerini Ophthalmic), a peptidomimetic inhibitor of the complement factor 5a receptor, blocks the mechanism that draws inflammatory cells into the disease process of age-related macular degeneration. When blocked, the numbers of neutrophils and macrophages decrease substantially and in turn the choroidal neovascularization also decreases.

Oral fenretinide (Sirion Therapeutics) is being investigated in a phase II study as a treatment for advanced geographic atrophy associated with age-related macular degeneration. It is hypothesized that this agent may limit disease progression by preventing delivery of circulating retinol to the eye, thereby reducing the accumulation of retinol-derived metabolites that are toxic to the retinal pigment epithelium and photoreceptor cells.