News

Salt Lake City-Research from the Moran Eye Center, University of Utah School of Medicine, Salt Lake City, showed that low ocular levels of the antioxidants lutein and zeaxanthin could contribute to age-related macular degeneration (AMD).

Orlando-Advancements in refractive surgery were the talk of Nidek's workshop on customized ablation at the American Academy of Ophthalmology (AAO) annual meeting here last fall. The symposium was intended as a forum for ophthalmologists to gain a better understanding of the technology available to them.

FDA Briefs

FDA OKs trials of laser reversal of presbyopia

New York-Pfizer Inc. and Eyetech Pharmaceuticals Inc. will jointly develop and commercialize Eyetech's pegaptanib sodium (Macugen) as a potential treatment for age-related macular degeneration (AMD) and diabetic macular edema (DME).

Indianapolis-Eli Lilly and Co. will delay the submission of its ruboxistaurin for the treatment of diabetic retinopathy and diabetic macular edema (DME) after two clinical trials failed to achieve satisfactory results on disease progression.

Orlando-A carefully designed comparison study has shown that the fixed combination of dorzolamide-timolol (Cosopt, Merck) is at least as effective as its concomitant components and might provide better trough control in some patients, said Stanley J. Berke, MD, FACS.

Orlando-The incidence of iris hyperpigmentation associated with unoprostone isopropyl ophthalmic solution 0.15% (Rescula, Novartis) was about 1% in two long-term studies, a rate that compares favorably with the incidence of 10% to 20% associated with latanoprost ophthalmic solution (Xalatan, Pharma-cia) in similar patient populations, reported Bernard E. McCarey, PhD.

Bimatoprost 0.03% (Lumigan, Allergan) offers more efficacy than latanoprost 0.005% (Xalatan, Pharmacia) for lowering elevated IOP and is similarly well tolerated, according to the results of a 6-month, multicenter, randomized, double-masked study.

Orlando-Although challenging to set up and conduct, studies that check glaucoma patients' IOP at intervals around the clock for 24 hours or longer provide valuable data about the ability of a medication to lower IOP and reduce fluctuation.

Orlando-Optical coherence tomography (OCT, Carl Zeiss Meditec) offers supe-rior sensitivity and specificity in detect-ing glaucoma and its progression, according to Boston glaucoma specialist Joel S. Schuman, MD.

Orlando-In scanning laser polarimetry (SLP), eye-specific correction of corneal polarization axis and magnitude can be obtained for the quantitative assessmentof the peripapillary retinal nerve fiber lay-er (RNFL) if macular-based strategies are used in eyes free of macular pathology, according to glau-coma specialist David S. Greenfield, MD.

Brimonidine tartrate 0.15% (Alphagan P, Allergan) is a "new and improved" version of brimonidine 0.2% (Alphagan, Allergan). It continues to have an efficacy profile similar to the one ophthalmologists have grown used to with brimonidine 0.2%.

Orlando-Optic nerve head (ONH) imaging forms an essential part of the management of suspected glaucoma, as well as in patients with established glaucomatous visual field loss, according to a London glaucoma specialist.

Fullerton, CA-An analysis of tear film function after LASIK and LASEK indicates patients fared equally in the two groups when LASEK was performed for high myopia.Tear film dysfunction seems to be best correlated to the depth of the ablation and not flap dimension, according to Robert Lingua, MD.

Manhasset, NY-In addition to being an effective mast cell stabilizer, pemirolast potassium ophthalmic solution 0.1% (Alamast, Santen) is soothing to the eyes, according to Peter D'Arienzo, MD.

Orlando-More than 30 ophthalmology residents are vying for top honors in the American College of Eye Surgeons' (ACES) 2003 Bloomberg Memorial Resident Videotape Competition for cataract/implant surgery.

The Selecta Duet (Lumenis), a new dual-purpose laser system, brings anterior segment surgeons a cost-effective and space-saving solution for treating both glaucoma patients undergoing selective laser trabeculoplasty (SLT) and pseudophakic patients in need of Nd:YAG laser capsulotomy for secondary cataract.

Sunnyvale, CA-Oculex Pharmaceuticals Inc. has completed patient enrollment in its phase II clinical trial of its lead product, Posurdex, for the treatment of persistent macular edema (PME).

New York-Using a doughnut and its hole in an analogy, David S. Greenfield, MD, said glaucoma specialists are now focusing on the doughnut rather than the hole-and retinal imaging advances have made this possible.

Expand your horizons

Mixing an optical dispensary with an ophthalmic practice used to border on being unethical. Today, however, many ophthalmologists who maintain an optical shop believe that it provides not only an added revenue center, but also offers more complete patient service.

The following awards were bestowed at the 2002 annual meeting of the American Academy of Ophthalmology (AAO) in recognition of outstanding service in a variety of fields.