News

In a phase IIa study of patients with neovascular age-related macular degeneration, a single subretinal injection of rAAV.sFlt-1 gene therapy demonstrated acceptable safety, but not a complete or durable anti-VEGF response. Additional preclinical research is under way.

Twenty-two of 23 eyes with a trans-scleral micro-lumen aqueous drainage tube implanted after failing maximum tolerated medication were evaluable at 3 years.

An ophthalmologist shares the clinical benefits he has experienced with a home vision-monitoring device for his patients with age-related macular degeneration.

People-like my neighbor and I-for centuries, have tended to give too much weight to negative news stories and gloomy predictions. Hence my resolution for 2016 to pay less attention to the doomsayers and pour more drinks for my friends.

Squalamine lactate-when combined with ranibizumab for treating neovascular age-related macular degeneration-achieved improved visual function when compared with the results achieved with ranibizumab treatment alone.

Two-year study results highlight some advantages of steroid treatment for DME.

David R. Chow, MD, provides an overview of new technological advancements for the vitreoretinal surgeon.

Pharmacotherapy research for diabetic macular edema is looking at targets other than VEGF inhibition to develop treatments that can be used as standalone intervention or may be complementary to current options.

The same photoactivation process used in collagen cross-linking for keratoconus can kill bacteria without the need for the oxygen responsible for the biomechanical effects, potentially pointing toward better treatments for keratitis, according to Olivier Richoz, MD, PhD.

The IRIS Registry can improve patient outcomes by giving physicians access to information that could identify potential areas of quality improvement based on their patient population.

Ophthalmology Times is pleased to announce Amelia Fong, MD, of Georgetown University School of Medicine, Washington, DC, as the second-place winner of the publication’s 2015 Resident Writer’s Award Program, sponsored by Allergan. Dr. Fong’s entry is featured here.

Swept-source microscope-integrated ocular coherence tomography is an investigational real-time imaging technique for monitoring and guiding anterior segment procedures.

A financial question that surfaces frequently, usually from physicians ages 55 years and older, is: “When and how should my spouse and I take our Social Security benefits?” These types of questions recently got complicated with the recent passage of new legislation by the U.S. Congress.

Acrylic expanders may be an option for the management of patients with congenital anophthalmos and microphthalmos.

Refractive laser platforms provide outstanding results, have reliable technology with excellent predictability and outcomes, and provide a broad range of applications. Better diagnostic imaging is possible with optical coherence tomography and Scheimpflug technology, and the advances of femtosecond lasers are moving into cataract surgery, said Michael Mrochen, PhD.

Take-home message: LASIK has continued to improve over time and will see further refinements thanks to better preop testing and technological advances.

Were he alive today, he would likely feel heartened by how his work has been carried on by Gerd U. Auffarth, MD, FEBO, who is now director of The David J Apple International Laboratory for Ocular Pathology at the University of Heidelberg, Germany.

Topical regenerating agent eye drops speed up the corneal healing and reduce ocular discomfort after the epi-off crosslinking but more research is needed.

Things that strike terror in the hearts of many Americans-spiders, earthquakes, Ebola virus disease, and politicians with plans to “fix” healthcare-don't faze me much. But, for as long as I can remember, I have had this visceral negative reaction to snakes.

Developments in the field of corneal biomechanics will enable refractive surgeons to perform more precise surgery in the future.

With myopia on the rise, greater understanding of genetic and environmental factors is needed to refine interventions that may curtail disease progression.

Proprietary technology enhances corneal smoothness that resulted in a shorter recovery time of the visual acuity, higher levels of postoperative visual quality, and shorter time to re-epithelialization.

In a prospective study including 20 presbyopic emmetropes, treatment with a proprietary topical ophthalmic formulation (PresbV Tears) demonstrated benefit for improving near, intermediate, and far uncorrected visual acuity.

Topography-guided LASIK is a new option for treatment of myopia with or without astigmatism.

An IOL “super formula” may broaden the conceptual understanding of IOL calculations, improve clinical outcomes for patients, and stimulate further progress in IOL formula research.

Three-year follow-up from the phase I/IIa trial of rAAV.sFlt-1 subretinal injection is encouraging for gene therapy for exudative age-related macular degeneration.

The unexpected discovery of viable Ebola virus in the eye of a patient who had recovered from the systemic disease has strengthened efforts to learn more about ophthalmic and systemic complications of Ebola survivors and has translated to management and follow-up strategies in West Africa.