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San Diego - Two-year follow-up of eyes with the ClariFlex with OptiEdge silicone IOL (AMO) implanted show that the second-generation silicone IOL with its novel edge design is performing well. Furthermore, risk of posterior capsular opacification (PCO) and glare was minimal, according to the results of a study presented by Elizabeth A. Davis, MD, FACS, at the annual meeting of the American Society of Cataract and Refractive Surgery.

Researchers around the world have been working diligently over the last 25 years to develop artificial corneas for patients who are not good candidates for the current techniques of keratoplasty, according to Eduardo C. Alfonso, MD.

More than 330 ophthalmologists from 24 states and several countriesattended "Glaucoma 2004: Mastering Tools and Techniques for the 21stCentury," on Friday, June 4, and Saturday, June 5, at the Plaza Hotel.

The use of antiproliferative agents has helped increase thelikelihood of successful filtering surgery by inhibiting the wound healingresponse. The problem is that these agents also contribute to the risk ofbleb leak and bleb-associated infection, reported Paul J. Lama, MD, of theUniversity of Medicine and Dentistry of New Jersey, Newark, and the Veterans'Administration Medical Center, East Orange, NJ.

Baltimore-Peripheral iris fixation of a foldable posterior chamber IOL using a modified McCannel suture appears to be a useful technique for the management of delayed-onset within-the-bag IOL subluxation in eyes with pseudoexfoliation syndrome, said Aruoriwo M. Oboh-Weilke, MD

Dorado, Puerto Rico-After positive results from a European clinical trial showed transforming growth factor-b2 (TGF-b2) mono clonal antibody was effective in delaying wound healing after first-time trabeculectomy, U.S. investigators are undertaking a multicenter clinical trial to compare the new agent with 5-fluorouracil (5-FU), reported Marshall N. Cyrlin, MD.

San Francisco-Clinical trials are under way in centers in Germany and Colombia to evaluate a dual-optic accommodating IOL (Synchrony, Visiogen) designed to offer amplified, consistent accommodation across a wide range of IOL powers, said Stephen D. McLeod, MD.

The Royale Injector (ASICO), a single-handed injection system for implanting the AcrySof lens (Alcon), has in- corporated a plunger mechanism into the design that cataract surgeons appreciate.

Dorado, Puerto Rico - Refractive lens exchange (RLE) does look promising as a viable option to corneal refractive procedures, particularly in those patients with high myopia or hyperopia. However, surgeons need to review the advantages and limitations of the intraocular procedure carefully with patients, according to Terrence P. O'Brien, MD.

Madison, WI-Leaking blebs occur fairly often now that antimetabolites are used in glaucoma surgery. A variety of treatment approaches can be used to manage them, and the outcomes are usually successful if care is taken in the management process, according to Todd Perkins, MD.