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Dorado, Puerto Rico-After positive results from a European clinical trial showed transforming growth factor-b2 (TGF-b2) mono clonal antibody was effective in delaying wound healing after first-time trabeculectomy, U.S. investigators are undertaking a multicenter clinical trial to compare the new agent with 5-fluorouracil (5-FU), reported Marshall N. Cyrlin, MD.

San Francisco-Clinical trials are under way in centers in Germany and Colombia to evaluate a dual-optic accommodating IOL (Synchrony, Visiogen) designed to offer amplified, consistent accommodation across a wide range of IOL powers, said Stephen D. McLeod, MD.

The Royale Injector (ASICO), a single-handed injection system for implanting the AcrySof lens (Alcon), has in- corporated a plunger mechanism into the design that cataract surgeons appreciate.

Dorado, Puerto Rico - Refractive lens exchange (RLE) does look promising as a viable option to corneal refractive procedures, particularly in those patients with high myopia or hyperopia. However, surgeons need to review the advantages and limitations of the intraocular procedure carefully with patients, according to Terrence P. O'Brien, MD.

Madison, WI-Leaking blebs occur fairly often now that antimetabolites are used in glaucoma surgery. A variety of treatment approaches can be used to manage them, and the outcomes are usually successful if care is taken in the management process, according to Todd Perkins, MD.

Mendoza, Argentina-Intraocular contact lenses (ICLs) (STAAR Surgical) have been used for many years outside the United States, and the results indicate that the ICLs can be tolerated over the long term. More patients have been opting to have this type of lens implanted following a previous LASIK procedure, and their visual outcomes have been good, according to Roberto Zaldivar, MD.

Carlsbad, CA-The Vision Membrane multifocal IOL (Vision Membrane Technologies Inc.) is a silicone anterior chamber phakic IOL that is intended to treat patients with myopia, hyperopia, and presbyopia. The IOL is extremely thin, even for cases of extreme myopia, and can eliminate the glare and halos normally associated with corneal refractive procedures.

Dorado, Puerto Rico-Have you ever wondered what you as a cataract surgeon can do to improve your patients' outcomes? Steve A. Arshinoff, MD, FRCSC, may have some answers.

At this year's ARVO meeting, glaucoma specialists can broaden their clinicalknowledge of topics ranging from surgery and wound healing to neuroprotectionto retinal nerve fiber layer imaging. Members of Ophthalmology Times'Editorial Advisory Board reviewed dozens of glaucoma abstracts to be presentedat the meeting. Some of the board's selections are highlighted here.

Anaheim, CA-Performing cataract surgery in an eye with a failing filtering bleb is a tricky business, which has been addressed by a few different procedures. Successful intervention can be achieved in carefully selected patients. However, in those in which intervention might be problematic, a new investigational device is under study to lower IOP, according to Reay H. Brown, MD.

Anaheim, CA-Selective laser trabeculoplasty (SLT) seems to be as effective for treating patients who had undergone argon laser trabeculoplasty (ALT) as the initial treatment for glaucoma, and may be more effective for re-treatments, but data and fol- low-up are limited, said Douglas N. Johnson, MD, at the annual meeting of the American Academy of Ophthalmology.

New Orleans-The AquaLase liquefaction device (Alcon) is a new technology for lens removal that provides the advantages of excellent safety for the cornea and posterior capsule without sacrificing efficiency, said Stephen F. Brint, MD.

Anaheim, CA-Myopic patients considering refractive lens exchange (RLE) for correcting their myopic refractive errors should be aware of the risk of retinal detachment (RD) and the retinal re-attachment rate and outcomes, said Barry S. Seibel, MD.

Anaheim, CA-Refractive lens exchange (RLE) for high hyperopia is another option for patients hoping to achieve a good refractive outcome and preserve the normal architecture of the cornea, said Raymond M. Stein, MD.

Washington, DC-Micro-thin prescription inserts (Intacs, Addition Technology), which received FDA approval in the United States in 1999 for the treatment of mild myopia, are an alternative to tissue-ablating laser vision procedures and have a number of advantages.