New Refractive EDOF IOL Tolerates Residual Refractive Error as Well as a Monofocal
Refractive miss is an unavoidable reality in cataract surgery, and among the persistent criticisms of premium IOLs is that their optical complexity makes them more sensitive to it. A prospective, multicenter, randomized study presented by Vance M. Thompson, MD, challenges that assumption for a new purely refractive EDOF IOL, specifically the TECNIS EDOF, in a head-to-head comparison against the TECNIS 1-piece Monofocal IOL.2
The trial enrolled 113 EDOF and 110 monofocal subjects at 9 US sites, with bilateral implantation and subject/evaluator masking. Defocus curves were generated at 6 months using a direct testing method across a range of +1.0 to –2.5 D. At ±0.25 and ±0.5 D of induced defocus, comparable proportions of EDOF and monofocal subjects—at least 94% in each group—maintained distance-corrected visual acuity of 20/25 or better, indicating closely matched tolerance to small refractive errors across both platforms.
The art and science of presbyopia correction: Navigating the IOL patient journey
Leading cataract surgeons Zach R. Balest, MD, and Lisa K. Feulner, MD, PhD, discuss their comprehensive approach to IOL counseling, exploring how they bridge expectation gaps and tailor premium lens strategies to each patient's unique anatomy, goals, and lifestyle.
The subgroup analysis, which focused on the 62 EDOF and 54 monofocal subjects who had an absolute postoperative spherical equivalent greater than 0.25 D in one or both eyes, is perhaps the more clinically relevant finding. Mean absolute spherical equivalent was similar between groups (0.40 ±0.27 D for EDOF; 0.36 ±0.23 D for monofocal). Despite that residual error, mean binocular uncorrected distance visual acuity was –0.01 ±0.08 logMAR for EDOF patients vs -0.04 ±0.11 logMAR for monofocal. Patient satisfaction and spectacle independence for distance were high in both groups: 97% vs 94% satisfied and 92% vs 87% not needing distance spectacle correction, respectively.
For surgeons counseling patients about realistic expectations with the refractive EDOF platform, these data offer a useful message: that even when the refractive target is not perfectly met, visual and satisfaction outcomes with this lens are comparable to a monofocal.
Vivity EDOF Delivers Strong Visual Outcomes and High Satisfaction After Myopic LASIK and PRK
The post-keratorefractive cataract patient has historically been approached with caution when it comes to premium IOL selection. Biometric uncertainty, altered corneal shape, and reduced tolerance for dysphotopsia have made many surgeons reluctant to offer diffractive multifocals in this population. Whether nondiffractive EDOF IOLs can thread that needle more comfortably is the question that Jimmy Y. Hu, MD, ABO, addressed in a prospective, noninterventional observational study of the Alcon Vivity IOL in patients with prior myopic LASIK or PRK. 3
The study analyzed 40 eyes from 24 patients (16 bilateral, 8 unilateral), with outcomes including monocular and binocular corrected and uncorrected acuities at distance, intermediate, and near, along with a defocus curve and the IOLSAT patient satisfaction questionnaire. The visual results were strong. Mean monocular corrected distance visual acuity was 0.009 ±0.042 logMAR, approximating 20/20. Mean binocular uncorrected distance visual acuity came in at approximately 20/22, with distance-corrected intermediate acuity at approximately 20/25, a particularly important metric given that intermediate vision is the primary functional advantage of EDOF over monofocal. Near vision was functional at approximately 20/40.
Spectacle independence at distance and intermediate was reported by 87.5% and 100% of binocular patients, respectively, though near spectacle independence was more modest at 43.75%, which is consistent with the known profile of EDOF IOLs that extend depth of focus without fully replacing near correction. Patient satisfaction was high overall, with 93.75% of participants saying they would choose the same lens again, a benchmark figure that is particularly meaningful in a population where premium IOL disappointment has historically been more common.
These results reinforce the emerging consensus that nondiffractive EDOF technology represents a well-suited option for the post-LASIK and post-PRK cataract patient who wants freedom from spectacles at distance and intermediate distances without accepting the photic phenomenon risk associated with diffractive designs.
VERACITY Planner and Total Keratometry Deliver Predictable Residual Astigmatism
Managing astigmatism at the time of cataract surgery in post-LVC eyes has long been complicated by the unreliability of standard keratometry in corneas with altered power distribution. Julie M. Schallhorn, MD, ABO, presented real-world outcomes from a large retrospective series that tested whether pairing IOLMaster 700 total keratometry with the Barrett True-K formula and VERACITY surgical planner could overcome that limitation.4
The study drew on 399 cataract cases from the VERACITY database, including a mix of monofocal (MON) and multifocal (MUL) toric IOLs and both with-the-rule (WTR) and against-the-rule (ATR) preoperative astigmatism patterns. The headline result was that mean postoperative cylinder across the full cohort was 0.48 ±0.45 D—a level of residual astigmatism that would likely be considered acceptable in routine cataract surgery, let alone in the more complex post-LVC context. Postoperative spherical equivalent was -0.14 ±0.54 D, and mean logMAR uncorrected distance visual acuity was 0.05 across all subgroups, approximating 20/22.
Importantly, outcomes were consistent regardless of IOL type or preoperative astigmatism direction. Residual cylinder was 0.50 D in the monofocal subgroup and 0.45 D in the multifocal subgroup, and 0.48 D in ATR and 0.46 D in WTR. The uniformity across these categories is clinically meaningful; it suggests that the combination of anterior and posterior keratometry with AI-assisted planning can neutralize many of the variables that have historically made toric IOL selection in post-LVC eyes unreliable.
For surgeons who have been hesitant to offer toric IOLs to post-LASIK and post-PRK patients, Schallhorn's series provides an evidence base for reconsidering that posture, provided appropriate biometric tools and planning platforms are in use.
REFERENCES
1. Zhou I, et al. Secondary Reverse Optic Capture for Temporal Negative Dysphotopsia in Eyes with Premium IOLs. Presented at: ASCRS 2026; April 10-13; Washington, DC.
2. Thompson V, et al. Comparative Tolerance to Refractive Error of a New Purely Refractive EDOF IOL vs. Standard Monofocal. Presented at: ASCRS 2026; April 10-13; Washington, DC.
3. Yu JY, et al. Cataract Surgery Visual Outcomes of a Non-Diffractive EDOF IOL in Eyes with Prior Myopic LASIK/PRK. Presented at: ASCRS 2026; April 10-13; Washington, DC.
4. Schallhorn J, et al. Refractive Outcomes after Cataract Surgery with Toric IOL in Patients with Prior Laser Vision Correction. Presented at: ASCRS 2026; April 10-13; Washington, DC.