Can't live with them, can't live without them
September 15th 2007There are three types of employees: climbers, quitters, and some who camp at mediocrity. Practice administrators who get to know their employees and what makes them tick will contribute to the success of the practice. It may be a matter of uncovering his or her true talents and finding the right place for that person within the practice.
Laser enhancement important adjunct to multifocal IOL
September 15th 2007The bar for refractive and vision outcomes has been raised in patients in whom multifocal IOLs have been implanted. Laser vision correction, therefore, has become an important enhancement tool. Multifocal IOL patients should be managed the same as laser vision refractive surgery patients, but additional issues should be considered.
Design differences of aspheric IOLs affect image quality
September 15th 2007When the performance of four different aspheric IOLs in scotopic light conditions was evaluated using a computer model, the results favored one three-piece lens (Tecnis, Advanced Medical Optics) for providing the best compromise between spherical and chromatic aberrations and depth of focus.
New potent difluprednate advances through phase III studies
September 15th 2007The potent corticosteroid difluprednate is being developed as an emulsion for topical use. Phase III clinical trials of the treatment of postoperative inflammation have been completed and a phase III study of anterior uveitis treatment is under way. Positive efficacy and safety results were achieved in phase III clinical trials in Japan.
Caution urged for nepafenac use for pain control after surface ablation procedures
September 15th 2007A prospective, randomized, contralateral eye-controlled study demonstrated that eyes treated with nepafenac 0.1% (Nevanac, Alcon Laboratories) for 4 to 5 days after PRK had significantly greater haze than eyes treated with ketorolac tromethamine 0.4% (Acular LS, Allergan). The study findings and similar experience of other surgeons raise questions about the safety of nepafenac use after surface ablation procedures.
Ophthalmic NSAIDs vary in amount, time needed to reduce inflammation
September 15th 2007Topical ophthalmic nonsteroidal anti-inflammatory drugs vary considerably in characteristics such as the number of days and the number of drops needed to reach the therapeutic endpoint. Although all are effective, doctors should learn to compare the NSAIDs based on their potency and penetration to make the best decisions for their patients.
Topical moxifloxacin efficacious in preventing endophthalmitis after intravitreal injection
September 15th 2007Results of testing in an animal model demonstrated that topical moxifloxacin 0.5% ophthalmic solution (Vigamox, Alcon Laboratories) provided effective prophylaxis against endophthalmitis following an intravitreal injection.
Nepafenac facilitates re-epithelialization and early pain reduction following PRK
September 15th 2007Nepafenac (Nevanac, Alcon Laboratories) administered three times daily after bilateral PRK, facilitated corneal healing that was comparable to ketorolac (Acular LS, Allergan) in a recently reported prospective, randomized, and double-masked study. In addition, pain relief occurred earlier in patients randomly assigned to receive nepafenac compared with patients who received ketorolac or bromfenac (Xibrom, ISTA Pharmaceuticals).
Malignant lesions of conjunctiva require appropriate management
September 15th 2007Appropriate management of malignant lesions of the conjunctiva requires detailed knowledge of the appearance and nature of the lesions. Here's how to recognize and treat the most common malignant lesions seen by ophthalmologists.
Study: older children more likely to develop strabismus, amblyopia
September 15th 2007No difference exists regarding the prevalence of amblyopia and strabismus in a population of Hispanic and African-American preschool children, and the prevalence of the two pathologies increases with age, according to findings of the Multi-Ethnic Pediatric Eye Disease Study.
DSEK upsurge likely due to high satisfaction, good visual results
September 15th 2007Descemet's stripping endothelial keratoplasty (DSEK) has changed the landscape in cornea surgery. Compared with those who have undergone penetrating keratoplasty, DSEK patients have an easier time postoperatively with rapid visual recovery. DSEK also affects decision-making about cataract extraction, and data appear to indicate that in most cases cataracts should be removed before DSEK or as a combined procedure.
Travoprost with less toxic preservative causes less ocular surface toxicity
September 1st 2007In a pooled dataset, the fixed combination of 0.2% brimonidine/0.5% timolol (Combigan, Allergan) showed greater reductions in IOP and a better tolerability profile than another combination agent, 2.0% dorzolamide/0.5% timolol (Cosopt, Merck). The twin advantages of greater pressure lowering and greater tolerability could help guide clinicians in choosing which therapy to choose when the initial treatment has not resulted in adequate improvement.
Fixed-combination solution reduces IOP at all time points
September 1st 2007Application of the fixed combination 2% dorzolamide hydrochloride/0.5% timolol maleate ophthalmic solution (Cosopt, Merck, Sharp & Dohme) resulted in a significant decrease in IOP 6 and 8 weeks after the onset of therapy in patients with ocular hypertension or primary open-angle glaucoma whose IOP had not been controlled by 0.5% timolol alone. The daytime and nighttime IOP values also were significantly reduced at the same time points compared with baseline.
Explaining benefits enhances acceptance of therapy
September 1st 2007Thorough patient education about anticipated side effects and benefits of treatment can improve patient acceptance of therapy and potentially increase adherence, concluded researchers who studied the effects of counseling intervention in patients treated with a prostaglandin analogue.
Travoprost with less toxic preservative causes less ocular surface toxicity
September 1st 2007An anti-glaucomatous medication formulated with a less toxic preservation causes less ocular surface toxicity, according to one cornea specialist. The development of travoprost ophthalmic solution 0.004% (Travatan Z, Alcon Laboratories), a prostaglandin analogue preserved with a new ionic-buffered preservative system (sofZia, Alcon Laboratories), seems to be the direction in which pharmaceutical companies will be moving in the future to eliminate harmful side effects caused by chronic application of anti-glaucoma medications.
Adjunctive brimonidine results in greater IOP lowering
September 1st 2007Results of a prospective, randomized, investigator-masked trial comparing brimonidine 0.15% with oxidative preservative (Purite) (Alphagan P, Allergan) and dorzolamide 2% (Trusopt, Merck) as adjuncts to latanoprost 0.005% (Xalatan, Pfizer) show the addition of either agent results in further IOP reduction, but the IOP-lowering effect was greater in the brimonidine/oxidative preservative group.