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Findings from immunohistochemical analysis of vascular endothelial growth factor (VEGF) receptor expression on pathology specimens of orbital vascular tumors suggest a potential therapeutic role for anti-VEGF agents.

Using an endoscope allows the clinician to visualize the tip of the probe and remove a pediatric nasolacrimal duct obstruction more easily, quickly, and accurately.

A retrospective study reviewing outcomes of 17 consecutive eyes with retinoblastoma treated for refractory vitreous seeds found intravitreal topotecan was safe and resulted in complete regression in all eyes after a mean of three injections.

When treating cases of pediatric orbital cellulitis, it is essential that clinicians consider the risks and advantages of antibiotics, steroids, and surgery.

Accommodating-disaccommodating IOLs are being developed that mimic the movement of the young crystalline lens through the use of “Zonular Capture Haptics” technology.

Though the year is quickly winding down, clinical education opportunities still abound for clinicians and vision researchers via the Association for Research in Vision and Ophthalmology (ARVO). For instance, a one-day public workshop will focus on the newest clinical data on inherited retinal diseases and future clinical trial designs aimed at developing therapies to stem vision loss.

Preoperative computer-assisted manipulation of CT images-with 3-D printing of anatomic models and intraoperative guides-can be a powerful tool in managing complex periorbital fractures, explains Paul Langer, MD.

A team of ophthalmic surgeons describes successful corneal neurotization using an ipsilateral supraorbital nerve in a patient with recalcitrant neurotrophic keratopathy

Thyroid eye disease (TED) is an autoimmune disease that is usually seen in patients with Graves’ thyrotoxicosis although it can also be seen in hypothyroid as well as euthyroid patients. Myasthenia gravis (MG) is also an autoimmune antibody mediated disorder characterized by fluctuating weakness of the skeletal muscles that can occur with TED.

Giovanni Staurenghi, professor of Ophthalmology at the University of Milan speaks about OCT, infrared, and autofluorescence base images used in practice. He explains how using blu autofluorescence imaging speeds up flow in cleaning and helps in diagnosis.

Infectious keratitis is not a common complication after laser vision correction (LVC), but it is important because it can be devastating, said Deepinder K. Dhaliwal, MD, at Refractive Surgery Subspecialty Day 2016.

If you want to become a better communicator, it’s important to become more sensitive not only to the body language and nonverbal cues of others, but also to your own.

Dr. Maling had a great idea for how to make the ophthalmology clinic more child-friendly.

The promise of simple, objective, single instrument-based screening for highly asymmetric keratoconus in patients considering LASIK is still more of an idea than reality. Multiple metrics can identify early keratoconus in a minority of affected eyes, but none of the metrics consistently identify early corneal abnormalities and none of the metrics identify the same eyes as being at elevated risk for ectatic disease.

Here’s a scenario: You walk up to the local fast food counter for lunch. The morning is still fresh in your mind, and all the afternoon projects are pushing their way into the forefront of your brain. Distracted is under stating where your mind is at. You finally get to the order person, and a 16-year-old sings out: “Hi sweetie, what can we do for you today?”

A retrospective study evaluating outcomes in patients with keratoconus found that when compared to femtosecond laser-enabled keratoplasty (FLEK), femtosecond laser deep anterior lamellar keratoplasty (FsDALK) had similar overall visual and refractive outcomes with a statistically significant lower overall graft rejection rate.

Patients with thin corneas as the result of keratoconus, ectasia following LASIK, or pellucid marginal degeneration can safely undergo epithelial-on collagen crosslinking with pulsed UV light and achieve visual benefits from the procedure.

Subclinical haze after CXL can affect corneal topography measurements; a comparison shows that measurements with four different devices cannot be used interchangeably.

Treating ocular surface disease may have an impact on the effectiveness of glaucoma treatment. Inder Paul Singh, MD, offers some strategies used in practice.

A focus on functional vision outcomes in patients who had both DMEK and DSAEK procedures found that the DMEK procedure yielded quality of vision superior to that of DSAEK.

Surgeons share their lessons learned about new lens technologies for refractive cataract surgery, such as extended-depth-of-focus IOLs.

The latest findings in the similarities between protein deposits seen in the eyes of patients with glaucoma and those with dementia are highlighted.

A single bimatoprost topical ring has been shown to be effective and safe for lowering IOP over six months, according to results from a phase II study.

In this column, I will describe various keratoconus case scenarios from my referral-based practice-ranging from the highly complex to simple-that can be improved with single or staged techniques that move patients toward emmetropia.

Five-year results from a study of the Boston keratoprosthesis type 1 implant suggest that frozen and fresh corneal donors offer similar clinical outcomes-with no significant differences in device retention, visual rehabilitation or complication rates.

An implantable corneal inlay recently approved by the FDA gives ophthalmologists a new choice in treating presbyopia.

At the 2016 Association for Research in Vision and Ophthalmology (ARVO) meeting in Seattle, about 100 uveitis and uveitis-related papers and posters were presented by researchers from around the world. The presentations covered a wide range of research initiatives that are underway to treat–or at least understand how to address–uveitis. Here are five intriguing abstracts of research that were presented at the meeting.