Editor, Ophthalmology Times
Palatin releases updated results from responder analyses of phase 3 Melody-1 trial in dry eye
Responder analysis was conducted to evaluate the percentage of patients achieving complete symptom resolution across 13 pre-specified symptom endpoints.
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Regeneron to highlight real-world efficacy of aflibercept 8 mg (EYLEA HD) in wAMD, DME, and DR
The company announced 27 abstracts at the Association for Research in Vision and Ophthalmology (ARVO) 2025 Annual Meeting from May 4 to 8 in Salt Lake City.
Bausch + Lomb identifies issue in enVista platform, returns product to market
Bausch + Lomb addresses recent IOL recall, ensuring safety with enhanced protocols and returning enVista lenses to market after thorough investigation.
Regeneron announces FDA issues CRL for aflibercept 8 mg (Eylea HD) sBLA
The FDA did not agree with a supplemental Biologics License Application for the addition of extended dosing intervals of up to 24 weeks across currently-approved indications.
Zhaoke enrolls first patient in phase 3 trial of cyclosporine ophthalmic gel for dry eye
CsA Ophthalmic Gel is an innovative cyclosporine gel being developed by Zhaoke in China for the treatment of moderate to severe DED.
50 years of visionary innovation: Leading ophthalmologists reflect on the field’s greatest breakthroughs
Celebrating a half-century of progress with Ophthalmology Times.
Regeneron’s sBLA for Eylea HD accepted for priority review by FDA
The sBLA seeks approval for Eylea HD for both the treatment of macular edema following retinal vein occlusion and broadening the dosing schedule to include every-4-week dosing across approved indications.
Study finds knowledge gaps in public understanding of glaucoma and cataracts
A survey collected demographic data, ocular and medical history, and responses assessing knowledge of glaucoma and cataracts in the Qassim region of Saudi Arabia.
Biocon reaches settlement agreement with Regeneron to launch aflibercept biosimilar, Yesafili, in the US
This agreement allows a launch in the US in the second half of 2026 or earlier in certain circumstances.
Eyestem releases positive results from phase 1 trial in patients with geographic atrophy
Eyecyte-RPE is a suspension of human induced pluripotent stem cell–derived retinal pigment epithelial cells.
Nextech and Ocuco partner to deliver seamless end-to-end eyecare platform
The partnership will integrate Ocuco’s optical software solution, Acuitas 3, with Nextech’s Ophthalmic Platform.
Vantage Biosciences doses first patient in phase 2 study of VX-01, oral therapy for nonproliferative diabetic retinopathy
VX01-DR-201, is a phase 2, multicenter, double-masked, randomized, placebo-controlled study in patients with moderate to severe NPDR without center-involved diabetic macular edema (CI-DME).
Pykus Therapeutics completes enrollment in trial evaluating PYK-2101
PYK-2101 is a focal hydrogel retinal sealant for use in patients undergoing surgery for a detached retina.
Opthea to lay off approximately 65% of company
The announcement follows the decision to discontinue the COAST and ShORe trials in wet age-related macular degeneration after the COAST trial failed to meet its primary end point.
FDA accepts biologics license application from Outlook Therapeutics for ONS-5010 for the treatment of wet AMD
A Prescription Drug User Fee Act (PDUFA) goal date of August 27, 2025, was set by the organization.
Alumis and Acelyrin file a definitive proxy statement for proposed merger
Each company will hold a respective special meeting of stockholders to vote on the approval of the merger.
Santen receives marketing authorization application approval from NMPA of China for tafluprost/timolol maleate (Tapcom) in patients with open-angle glaucoma
Tapcom is a preservative-free, fixed-combination eye drop of tafluprost 0.0015% and timolol 0.5% for lowering intraocular pressure.
Part 6: Biggest innovations in ophthalmology in 50 years
In celebration of Ophthalmology Times' 50th anniversary, we asked leading experts in the field what they see as the biggest innovation in ophthalmology in the past 5 decades.
Part 5: Biggest innovations in ophthalmology in 50 years
In celebration of Ophthalmology Times 50th anniversary, we asked leading experts in the field what they see as the biggest innovation in ophthalmology in the last 5 decades.
Part 4: Biggest innovations in ophthalmology in 50 years
Doctors warn TikTok & Instagram reels may be damaging eyes long-term
Recent estimates show that there are over 2 billion users on Instagram, of which over 726.8 million interact with reels on the platform.
Avisi Technologies releases 6-month interim results from VITA trial
The trial is designed to assess the safety and effectiveness of Avisi Technologies' investigational VisiPlate device in patients with open-angle glaucoma.
FDA issues Complete Response Letter to Aldeyra Therapeutics for resubmitted New Drug Application of reproxalap
The company stated that the FDA noted at least one additional adequate and well controlled study to demonstrate a positive effect on the treatment of ocular symptoms of dry eye should be conducted.
Part 3: Biggest innovations in ophthalmology in 50 years
OKYO Pharma releases positive long-term stability data for urcosimod in neuropathic corneal pain
Urcosimod (formerly known as OK-101) has been shown to be stable for over 2 and a half years in single-use ampoules used for administration of the drug to patients.
Opthea discontinues COAST and ShORe trials in wet AMD
The decision to discontinue the trials comes shortly after the announcement that COAST missed its primary endpoint.
Part 2: Biggest innovations in ophthalmology in 50 years
Part 1: Biggest innovations in ophthalmology in 50 years
Labtician Ophthalmics announces commercial launch of Lab TRIACTIV
Lab TRIACTIV is powered by “advanced cationic liposomal technology” for dry eye relief.
Pantheon Vision and Eyedeal Medical enter collaborative agreement to develop bioengineered corneal implant
Pantheon Vision’s bioengineered corneal implant aims to tackle issues with the success rate of human donated tissue.