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Commentary|Articles|October 19, 2026

Beyond slowing atrophy: Optogenetic therapy targets vision lost to GA

Jordi Monés, MD, PhD, explains why RP and Stargardt data support testing son-vec to restore vision in advanced GA.

The 2 complement inhibitors approved by the US Food and Drug Administration (FDA) for geographic atrophy (GA) secondary to age-related macular degeneration (AMD) slow lesion growth, but neither restores vision that has already been lost. Optogenetic gene therapy is designed to address that gap.

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