Ocular agent provides prolonged pruritus prophylaxis
May 1st 2003Boston-The mast-cell stabilizer pemirolast potassium 0.1% (Alamast, Santen) is a safe, comfortable, and effective agent for preventing and relieving ocular itching of seasonal allergic conjunctivitis throughout the allergy season, according to a pooled analysis of data from phase III trials.
Corticosteroid shown to be safe for long-term SAC control
May 1st 2003Tampa, FL-Loteprednol etabonate ophthalmic suspension 0.2% (Alrex, Bausch & Lomb Pharmaceuticals and Pharmos Corp.), the first corticosteroid specifically designed for signs and symptoms of seasonal allergic conjunctivitis (SAC), is safe for long-term use, according to a recent multicenter study.
Early allergy season springs into action
May 1st 2003This year's fierce winter is now about to bring a big dose of misery to the 60 million Americans who suffer from seasonal allergies. Experts predict a fast-peaking, intense spring allergy season. Moisture accumulated from heavy snow and excessive rain has nurtured mold, and will fuel tree-pollen production-all of which will trigger an early and severe allergy season.
New guidelines focus on medical management of glaucoma
May 1st 2003Maui, HI-Evidence-based guidelines for the medical management of glaucoma developed by a panel of glaucoma specialists aim to enhance clinical decision-making for the general ophthalmologist, said Anne L. Coleman, MD, PhD, at the annual Royal Hawaiian Eye meeting here.
Hyperhomocysteinemia may be risk factor for exfoliation syndrome
May 1st 2003S?o Paulo, Brazil-Hyperhomocysteinemia appears to be associated with exfoliation syndrome and might be a modifiable risk factor for that disorder, said Roberto M. Vessani, MD, who was a glaucoma fellow with Glaucoma Associates of New York and is currently glaucoma preceptor, glaucoma service, department of ophthalmology, University of S?o Paulo, Brazil.
ASCRS survey LASIK continues to be predominant
May 1st 2003San Francisco-LASIK continues to be the predominant refractive procedure for treating patients with refractive errors ranging from +3 to -9 to -10 D, according to Richard J. Duffey, MD, who presented the results of the 2002 ASCRS survey of U.S. trends in refractive sur-gery.
TTT trial to test potential treatment for wet AMD
May 1st 2003Mountain View, CA-IRIDEX Corp. has completed enrollment in a clinical trial for its TTT4CNV, to determine whether trans-pupillary thermotherapy (TTT) laser treatment can reduce the risk of vision loss for patients with occult wet age-related macular degeneration (AMD).
ISTA to try again after FDA panel rejects Vitrase
May 1st 2003Irvine, CA-ISTA Pharmaceuticals is regrouping after an FDA advisory committee said the company's tests of ovine hyal-uronidase (Vitrase) failed to demonstrate sufficient statistical evidence to support its efficacy in treating vitreous hemorrhage.
Allergan begins launch of cyclosporine
May 1st 2003Irvine, CA-In early April, cyclosporine ophthalmic emulsion 0.05% (Restasis, Allergan) became commercially available for the treatment of eye inflammation associated with keratoconjunctivitis sicca. The introduction of the product marks the first therapeutic option for people with dry eye by not only providing temporary relief of dry eye, but also treating the associated ocular inflammation, according to the company.
Anti-VEGF treatment shows promise in preliminary trials
April 15th 2003Boston-Multiple intravitreal injections of rhuFab V2 (Genentech Inc., San Francisco) are well-tolerated and appear to have favorable biologic activity for the treatment of exudative age-related macular degeneration (AMD), said Jeffrey S. Heier, MD, of Ophthalmic Consultants of Boston and the Center for Eye Research, principal investigator for that trial.
OCT useful for detecting vitreofoveal traction, thickness
April 15th 2003Royal Oak, MI-Optical coherence tomography (OCT) may be more sensitive than fluorescein angiography in detecting vitreofoveal traction and differences in thickness in the different areas of the macula in patients with persistent diabetic macular edema (DME). While fluorescein angiography remains the standard in imaging, Cynthia Carvalho-Recchia, MD, suggested an adjunctive role for OCT in patients with DME.
Breakthrough seen in canine Leber's congenital amaurosis
April 15th 2003Philadelphia-Gene therapy has successfully restored the visual function of blind dogs with a rare congenital retinal disease, according to early research results. This breakthrough holds implications for the treat- ment of several human retinal degenerative diseases within the next several years.
PRK okay for U.S. Army Special Forces using night vision goggles, study concludes
April 15th 2003Washington, DC-PRK causes no loss of visual resolution and, in fact, improves uncorrected visual acuity (UCVA) and visual resolution during use of night vision goggles under a range of night sky conditions.