News

Fort Lauderdale, FL-In a comparison study of three fluoroquinolones, gatifloxacin ophthalmic solution 0.3% (Zymar, Allergan), a new fourth-generation compound, was the most effective agent in the treatment of Mycobacterium chelonae keratitis after lamellar keratectomy in an animal model.

Fort Lauderdale, FL-Topical loteprednol etabonate 0.5% (Lotemax, Bausch & Lomb) instilled four times daily may be beneficial to treat patients who have keratoconjunctivitis sicca (KCS) with at least a moderate inflammatory component.

Duluth, GA-Diclofenac sodium ophthalmic solution (Voltaren, Novartis Ophthalmics) is a nonsteroidal anti-inflammatory drug (NSAID) with a proven track record. It is the drug of choice to relieve pain following cataract or refractive surgery, and it has maintained that position despite the increased incidence of corneal melt associated with a generic version of the drug, according to Douglas A. Katsev, MD. He described diclofenac as a staple in his private practice in Santa Barbara, CA.

Fort Lauderdale, FL-Reformulated ketorolac tro-methamine ophthalmic solution 0.4% (Acular LS, Allergan) is a safe and effective topical nonsteroidal anti-inflammatory drug (NSAID) for treating ocular pain after PRK.

Ashland, OH-Less than 2 hours by air from the sun-drenched beaches of Miami lay countries where impoverished people have never seen a doctor. In the Dominican Republic and Honduras, where electricity is unreliable and roads are often impassable, congenital glaucoma blinds children and cataracts grow rock hard. Diabetes robs young and old of their limbs, jobs are scarce, and mail and garbage service are nonexistent. Most adults carry machetes for protection.

In the ophthalmic market, there is a distinctive gap between industry leaders and followers.

Munich, Germany-The 2003 annual gathering of the European Society of Cataract and Refractive Surgeons (ESCRS) will open on Saturday, Sept. 6 and continue through Wednesday, Sept. 10, at the ICM Congress Centre, in this city in the heart of Bavaria.

San Francisco-Automatic iris registration is the basis for the next-generation registration and tracking technology and represents a superior technique for cyclotorsional compensation, said Marc G. Odrich, MD, at the annual meeting of the American Society of Cataract and Refractive Surgery.

Boston-Genetic researchers are trying to identify the genetic causes of several conditions that seem to predispose individuals to secondary glaucomas, according to Janey Lee Wiggs, MD, PhD. She reviewed the current knowledge of the molecular genetics of the secondary glaucomas.

Scotland can claim fame for a number of talented surgeons of the 18th and 19th centuries, all with the same family name, Bell. Their medical contributions spanned 2 centuries.

Fort Worth, TX-With the recent FDA approval of its foldable, ultraviolet (UV)-, and blue-light-filtering IOL, Alcon believes its AcrySof Natural single-piece lens has the potential to set a new standard in IOLs.

Irvine, CA-When treating dry eye at all levels of severity, ophthalmic professionals need to match appropriate therapies with individual patients' needs.

New York-With the recent acquisition of Pharmacia Corp., Pfizer Inc. is making latanoprost ophthalmic solution (Xalatan) and three non-ophthalmic medicines available at a reduced cost to qualified senior citizens.

New York-Robert Ritch, MD, surgeon, director, and chief of glaucoma services at The New York Eye and Ear Infirmary, will serve a 5-year term as a trustee of the Association for Research in Vision and Ophthalmology (ARVO).

Basel, Switzerland-Novartis Ophthalmics will have exclusive license to develop and market ranibizumab (Lucentis, formerly known as rhuFab V2), an anti-VEGF antibody fragment, outside North America under a new agreement with Genentech Inc.

Irvine, CA-Allergan's Botox (botulinum toxin type A) has officially made its way into the nation's lexicon as a household word.

Monrovia, CA-The FDA is studying STAAR Surgical Co.'s implantable contact lens (ICL) under an expedited review status that calls the product a potentially revolutionary advance over the current market.

Chicago-In a series of formal lectures, panel discussions, mini-workshops, and Q&A sessions at "Glaucoma 2003," glaucoma experts summarized recent information on new imaging and perimetry technologies, treatment modalities, clinical trial findings, and the management of challenging glaucoma cases and surgical complications with a focus on applications to daily patient care.

Atlanta-The FDA is reviewing a pre-market notification from CIBA Vision Corp. for an epikeratome device for use in sub-epithelial separation.

Fort Lauderdale, FL-Gatifloxacin ophthalmic solution 0.3% (Zymar, Allergan) shows clearly improved activity against commonly encountered gram-positive ocular bacteria in vitro compared with older fluoroquinolones. This fourth-generation fluoroquinolone received FDA approval in March (see related article, Ophthalmology Times, May 1 issue, Page 1).

Fort Lauderdale, FL-What constitutes glaucoma progression and the relationship between progressive structural and functional injury? These were the main questions researchers set out to answer during a glaucoma mini-symposium at the annual meeting of the Association for Research in Vision and Ophthalmology.

Fort Lauderdale, FL-In the short term, intravitreal triamcinolone acetonide (4 mg) reduces the risk of progressive loss of vision and commonly improves vision in patients with diabetic cystoid foveal edema that persists after laser treatment, said Mark C. Gillies, MD, PhD, at the annual meeting of the Association for Research in Vision and Ophthalmology.

Before mailing that next first-class letter, take a close look at the photo featured on the postage stamp; it just might be that of a brown pelican-the handiwork of one James D. Brandt, MD.

When Charles A. Kirby, MD, wanted to learn more about expanding his practice with conductive keratoplasty (CK), he did more than read about the procedure and attend seminars. He took a cue from a popular television game show to "phone a friend."

San Francisco-A novel accommodating IOL (FlexOptic, Quest Vision) designed to mimic the natural crystalline lens through an ability to change optic sphericity is a promising new alternative to treating presbyopia, with the potential for superior efficacy and safety relative to other options for surgical accommodative correction, said John D. Hunkeler, MD, at the American Society of Cataract and Refractive Surgery annual meeting.

San Francisco-For appropriately selected patients undergoing cataract surgery, implantation of a foldable, multifocal IOL (Array SA40 IOL, AMO) is the best available solution for providing good uncorrected near and distance vision, said Roger Onnis, MD, at the American Society of Cataract and Refractive Surgery annual meeting.

Fort Lauderdale, FL-Intravitreal injection of triamcinolone acetonide (Kenalog, Bristol-Myers Squibb) may be a safe and effective treatment for central retinal vein occlusion (CRVO), said Michael S. Ip, MD, at the annual meeting of the Association for Research in Vision and Ophthalmology.

Fort Lauderdale, FL-In eyes with predominantly classic subfoveal choroidal neovascularization (CNV) treated with photo- dynamic therapy (PDT) using verteporfin (Visudyne, Novartis Ophthalmics), vision remained stable and the need for additional treatment decreased dramatically over time, reported Peter K. Kaiser, MD, at the annual meeting of the Association for Research in Vision and Ophthalmology.

Fort Lauderdale, FL-Efforts to develop an episcleral anecortave acetate transscleral drug delivery system (AA-TSDDD), targeted for patients with age-related macular degeneration (AMD), are progressing initially in the rhesus monkey as preliminary devices are being redesigned to decrease postoperative problems, said Timothy W. Olsen, MD.

Fort Lauderdale, FL-A 4-day course of moxifloxacin ophthalmic solution 0.5% (Vigamox, Alcon) is a safe and effective treatment for bacterial conjunctivitis in adults and children as young as 1 month old, according to results from a phase III FDA study, reported Harold R. Katz, MD, who spoke on behalf of the Moxifloxacin Conjunctivitis Study Group at the annual meeting of the Association for Research in Vision and Ophthalmology. The fourth-generation fluoroquinolone received FDA approval in April for the treatment of bacterial conjunctivitis (see related article, Ophthalmology Times, June 1, 2003 issue, Page 1).