Patients with wet age-related macular degeneration in Canada experience inflammation
January 15th 2009Ophthalmologists in Canada are hoping that an outbreak of ocular inflammation in patients being treated with bevacizumab (Avastin, Genentech) will not cause stricter regulations against its off-label intravitreal use or deter doctors from using it to treat wet age-related macular degeneration. All of the confirmed cases were linked to a specific lot of the drug that was distributed throughout Canada and other parts of the world. Health Canada currently is working with an independent laboratory to complete tests to determine the cause of the outbreak.
Abbott and AMO reach acquisition agreement
January 12th 2009Abbott and Advanced Medical Optics (AMO) announced in a joint prepared statement that an agreement has been reached for Abbott to acquire AMO for $22 per share in cash, for a total transaction value of approximately $2.8 billion, inclusive of estimated net debt at the time of closing, approved by both boards of directors.
X-GEN receives go-ahead for acetazolamide for glaucoma
January 6th 2009X-GEN Pharmaceuticals Inc. will begin marketing injectable acetazolamide for indications including open-angle glaucoma and secondary glaucoma as well as preoperative use for the treatment of acute angle-closure glaucoma in cases in which surgery has been delayed to lower IOP.
Aspheric optic lens favorable in early clinical experience
January 1st 2009In cataract surgery cases where implantation of a monofocal acrylic IOL is planned, a recently approved model (Akreos Advanced Optics Aspheric Lens [model AO60], Bausch & Lomb) has rapidly become the IOL of choice for one surgeon who has implanted almost 100 of the lenses.
Corneal transplantation surgery enters new era with new techniques
January 1st 2009Anatomic outcomes of penetrating keratoplasty (PKP) have improved thanks to a number of innovations, but functional outcomes have still been suboptimal. The development of techniques based on use of the femtosecond laser to create host and donor incisions has driven PKP into a new era of refractive surgery.
Toric IOL shown to be rotationally stable by new imaging system and software
January 1st 2009A proprietary toric IOL (AcrySof Toric, Alcon Laboratories) was found to be rotationally stable and a reliable option for the correction of astigmatism in a prospective study of 50 patients. The results were arrived at by using an innovative digital imaging technique coupled with new software that uses a grid to determine rotational stability of IOLs to a sensitivity of 0.1°. The implications of the new digital imaging technology and its associated software extend well beyond the findings in these 50 patients.
Mechanical microkeratome performance highlighted in clinical, cadaveric studies
January 1st 2009A mechanical microkeratome (One Use-Plus SBK, Moria) created flaps with predictable dimensions that were planar and associated with extremely smooth stromal beds, and patients benefited with rapid visual recovery, in a clinical trial including 50 eyes as well as cadaveric eyes. The microkeratome was compared with a 60-kHz femtosecond laser (IntraLase, Advanced Medical Optics) in the study.
Aspheric toric bifocal IOL plus co-axial microincisional surgery is 'successful'
January 1st 2009An aspheric implant (Acri.LISA Toric 466 TD IOL, Carl Zeiss Meditec) corrects astigmatism and presbyopia and can be implanted through a >1.5-mm incision to avoid surgically induced astigmatism and minimize induced aberrations. The optic is designed for optimal visual quality and the haptics for rotational stability. Excellent outcomes, including high patient satisfaction, have been achieved implanting this IOL after co-axial microincisional surgery using a phacoemulsification platform (Oertli).
Multifocal IOL mixing, matching shows good results in European study
January 1st 2009Mixing and matching IOLs with different optical principles was investigated in a European multicenter project. Data from 90 patients seen at 120 to 180 days after surgery showed excellent results in functional outcomes, patient satisfaction, and spectacle independence.
Femtosecond lasers: A broadening product category with expanding applications and advanced features
January 1st 2009Five femtosecond lasers are now commercially available. They vary in their features and capabilities, but the product category as a whole is characterized by a rapid evolution toward improved technology with more changes and a growing list of uses expected in the future.
Post-LASIK night-driving visual performance shows changes
January 1st 2009Wavefront-guided LASIK was associated with better night-driving performance than conventional LASIK in two studies conducted in a night-driving simulator. The better outcomes following wavefront-guided procedures could be attributable to fewer higher-order aberrations and use of a femtosecond laser.
Foldable phakic IOL shows positive outcomes
January 1st 2009The angle-supported phakic IOL (AcrySof, Alcon Laboratories) is being evaluated for the treatment of moderate to high myopia in three phase II and III clinical trials in Europe and North America enrolling 360 patients. Data from a 3-year visit in 104 eyes show excellent stability, predictability, and vision outcomes with a low rate of adverse events.