RIDE, RISE phase III results favorable for DME treatment
July 15th 2014The open-label extension RIDE and RISE phase III studies of ranibizumab (Lucentis, Genentech) indicated that the beneficial results of the drug for treating diabetic macular edema were maintained over the long-term with less than monthly follow-up or injection treatment.
Long-term gene therapy for wet AMD promising
July 15th 2014The first results from a phase I trial of gene therapy for exudative age-related macular degeneration using a subretinal injection suggest that the treatment is safe and well tolerated even in the elderly population and may eliminate the need for frequent reinjection with anti-vascular endothelial growth factor agents.
Nicox to acquire Aciex Therapeutics
July 8th 2014Nicox S.A. has signed an agreement to acquire all of the outstanding equity of Aciex Therapeutics, a private, U.S.-based, ophthalmic development pharmaceutical company with a pipeline of therapeutics addressing the ophthalmic market, including allergy and inflammation.
Iluvien receives positive approval from 10 more countries
July 3rd 2014Alimera Sciences' sustained-release intravitreal implant (Iluvien)-its treatment of chronic macular edema-has received a positive outcome of the Repeat-Use Procedure with the Medicines and Healthcare products Regulatory Agency of the United Kingdom serving as the Reference Member State.
Dynamics of dry eye evaluation changing as options expand
July 1st 2014A healthy, stable tear film is essential for high quality visual function and stable interblink vision. If patients have dry eye disease, it must be successfully resolved before corneal refractive surgery takes place. Similarly, patients who do not have preoperative dry eye but are at high risk of developing the disease postoperatively also need special attention.
Akorn forced to sell marketing rights to 5 drugs
July 1st 2014The Federal Trade Commission (FTC) is requiring Akorn Enterprises’ subsidiary Hi-Tech Pharmacal to sell the marketing rights for five generic drugs to Watson Laboratories to settle federal charges that Akorn’s acquisition of Hi-Tech was anticompetitive.
Novel design for pupil dilation device expands realm of surgical options
July 1st 2014A novel device for pupil dilation offers several advantages over current devices, including the ability to be inserted through smaller sizes and lesser numbers of incisions in procedures, noted its inventor, Suven Bhattacharjee, MS, DO, DNB, FRF.
Aberrometry with streaming refractive data enhances results
July 1st 2014Analyses of refractive prediction error in a study including 262 eyes implanted with a variety of pseudophakic IOLs shows benefit for using intraoperative aberrometry with streaming refractive data (ORA System with VerifEye, WaveTec Vision).
Phaco without presbyopic inlay explantation viable option
July 1st 2014Two patients underwent cataract surgery and implantation of a monofocal IOL with a small aperture corneal inlay (Kamra, AcuFocus) in place. The surgery was uneventful, presented no new technical challenges, and resulted in spectacle-free near, intermediate, and distance vision.
Efficiency of radiused, non-radiused tips for phaco explored in study
July 1st 2014Radiused and non-radiused phacoemulsification tips were equivalent in efficiency for removing lens fragments during micropulse longitudinal and transversal/longitudinal phacoemulsification procedures. Non-radiused tips were more efficient with torsional action.
Comparing conventional limbal relaxing incisions, femtosecond laser
July 1st 2014Intraoperative aberrometry readings can be useful in reducing astigmatism when used with either conventional diamond blade limbal relaxing incisions and femtosecond laser arcuate incisions. In a study of 50 eyes, no statistically significant difference was found between two groups of patients in postoperative mean residual astigmatism.
Laser versus manual cataract surgery
July 1st 2014In a randomized study including 65 patients undergoing femtosecond laser-assisted or standard phacoemulsification, there were no significant differences between groups in central corneal thickness or endothelial cell loss at 1 week or 1 month postsurgery.