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Findings from a single-surgeon consecutive series including 97 eyes with up to 12 years of follow-up provide realistic insights for corneal surgeons about long-term outcomes after implantation of the Boston keratoprosthesis type 1 (“Boston KPro”; Massachusetts Eye and Ear Infirmary). The information-which included analyses of visual acuity results, device retention rates, and complications associated with the permanent keratoprosthesis-was presented by Anthony J. Aldave, MD, at Cornea 2016.

Adding a topical nonsteroidal anti-inflammatory drug (NSAID) to treatment with a topical corticosteroid significantly reduces the incidence of clinical pseudophakic cystoid macular edema (PCME) in at-risk eyes.

Under the best of circumstances-meaning when cataract surgery is performed in an eye with a normal cornea by expert hands and with use of an advanced IOL power calculation formula-the achieved refractive outcome will be more than 0.5 D off target in 1 out of every 11 eyes.

Recognizing that healthcare errors impact one in every ten patients around the world, the World Health Organization has called patient safety an endemic concern, said Richard L. Abbott, MD, at AAO 2016.

Findings from immunohistochemical analysis of vascular endothelial growth factor (VEGF) receptor expression on pathology specimens of orbital vascular tumors suggest a potential therapeutic role for anti-VEGF agents.

A retrospective study reviewing outcomes of 17 consecutive eyes with retinoblastoma treated for refractory vitreous seeds found intravitreal topotecan was safe and resulted in complete regression in all eyes after a mean of three injections.

Though the year is quickly winding down, clinical education opportunities still abound for clinicians and vision researchers via the Association for Research in Vision and Ophthalmology (ARVO). For instance, a one-day public workshop will focus on the newest clinical data on inherited retinal diseases and future clinical trial designs aimed at developing therapies to stem vision loss.

Preoperative computer-assisted manipulation of CT images-with 3-D printing of anatomic models and intraoperative guides-can be a powerful tool in managing complex periorbital fractures, explains Paul Langer, MD.

Thyroid eye disease (TED) is an autoimmune disease that is usually seen in patients with Graves’ thyrotoxicosis although it can also be seen in hypothyroid as well as euthyroid patients. Myasthenia gravis (MG) is also an autoimmune antibody mediated disorder characterized by fluctuating weakness of the skeletal muscles that can occur with TED.

Giovanni Staurenghi, professor of Ophthalmology at the University of Milan speaks about OCT, infrared, and autofluorescence base images used in practice. He explains how using blu autofluorescence imaging speeds up flow in cleaning and helps in diagnosis.

Infectious keratitis is not a common complication after laser vision correction (LVC), but it is important because it can be devastating, said Deepinder K. Dhaliwal, MD, at Refractive Surgery Subspecialty Day 2016.

The promise of simple, objective, single instrument-based screening for highly asymmetric keratoconus in patients considering LASIK is still more of an idea than reality. Multiple metrics can identify early keratoconus in a minority of affected eyes, but none of the metrics consistently identify early corneal abnormalities and none of the metrics identify the same eyes as being at elevated risk for ectatic disease.

Here’s a scenario: You walk up to the local fast food counter for lunch. The morning is still fresh in your mind, and all the afternoon projects are pushing their way into the forefront of your brain. Distracted is under stating where your mind is at. You finally get to the order person, and a 16-year-old sings out: “Hi sweetie, what can we do for you today?”

A retrospective study evaluating outcomes in patients with keratoconus found that when compared to femtosecond laser-enabled keratoplasty (FLEK), femtosecond laser deep anterior lamellar keratoplasty (FsDALK) had similar overall visual and refractive outcomes with a statistically significant lower overall graft rejection rate.

Patients with thin corneas as the result of keratoconus, ectasia following LASIK, or pellucid marginal degeneration can safely undergo epithelial-on collagen crosslinking with pulsed UV light and achieve visual benefits from the procedure.

Subclinical haze after CXL can affect corneal topography measurements; a comparison shows that measurements with four different devices cannot be used interchangeably.

A focus on functional vision outcomes in patients who had both DMEK and DSAEK procedures found that the DMEK procedure yielded quality of vision superior to that of DSAEK.

In this column, I will describe various keratoconus case scenarios from my referral-based practice-ranging from the highly complex to simple-that can be improved with single or staged techniques that move patients toward emmetropia.