Clinical clues shine light on differences between Sjögren’s Syndrome and Meibomian Gland Dysfunction in DED.
A multifactorial disease with numerous etiologies, diagnosing the underlying causes of dry eye disease can be a key step in successful management.
Now, a pair of surveys could provide some additional insight for patients who present with issues that could prove to be dry eye, including the surveys include the ocular surface disease index (OSDI) or the Standard Patient Evaluation of Eye Dryness Questionnaire (SPEED).
The OSDI and SPEED questionnaires cannot be used interchangeably. Finis et. al. noted that SPEED levels seemed to correlate more with the parameters of evaporative dry eye, the OSDI values correlate more with parameters of aqueous tear-deficient dry eye. 1
In SPEED, a score of 0 to 4 indicates mild dry eye, 5 to 7 indicates moderate dry eye, and 8 and greater indicates severe dry eye.
The majority of evaporative dry eye is caused by meibomian gland dysfunction (MGD), while autoimmune diseases, such as Sjögren’s syndrome, are frequently responsible for aqueous-deficient dry eye. MGD and Sjögren’s have different clinical signs, but the presenting symptoms are often similar.
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