News

Article

The Retinal Degeneration Fund announces investment in Amber Bio

Author(s):

Amber Bio is developing a first-of-its-kind RNA writing platform using multi-kilobase edits to reach previously undruggable patient populations.

(Image Credit: AdobeStock/thesweetsheep)

(Image Credit: AdobeStock/thesweetsheep)

The Retinal Degeneration Fund, the venture arm of the Foundation Fighting Blindness, announced its participation in a $26 million Series Seed financing for Amber Bio to support its RNA-editing platform.

According to a Foundation Fighting Blindness news release, Amber is leveraging a multi-kilobase RNA editing platform to expand the reach of treatable pathogenic variants.

The foundation noted in its news release the seed financing was driven by Playground Global and Andreessen Horowitz Bio + Health. Lilly Venture Sciences, Hummingbird Ventures, and Pillar VC also participated in the round alongside the RD Fund.

Jacob Borrajo, PhD, CEO, and co-founder at Amber Bio, said the company is pleased to be partnering with RD Fund and the Foundation Fighting Blindness to develop therapeutics to overcome retinal disorders.

“This partnership brings world-renowned experts in retinal biology and retinal therapeutic development to join in Amber Bio's mission,” he said in the news release.

The funding will be used to advance a first-of-its-kind RNA editing platform which enables multi-kilobase edits, allowing a single drug to treat diseases with high allelic diversity. Among other therapeutic areas, Amber Bio is interested in applying its technologies toward inherited retinal diseases that arise from a diverse set of mutations.

Rusty Kelley, PhD, managing director at the RD Fund, cited its desire to be a part of a strong, diverse syndicate to support Amber's skilled leadership team and their ability to design and improve a novel system for rewriting RNA,

“The retina transcriptome that includes larger genes with many disease-causing variants is ripe for accurate, efficient and durable RNA targeting, and with reduced toxicity that may result from genomic editing,” he said in the news release.

About the RD Fund

According to the news release, the Retinal Degeneration Fund is the venture arm of the Foundation Fighting Blindness, and a leading investor in the retinal disease space. It was formed in 2018 to serve the foundation's mission to rapidly drive research toward preventions, treatments, and cures for the entire spectrum of blinding retinal diseases including retinitis pigmentosa, macular degeneration, and Usher syndrome. The RD Fund focuses on mission-related investments in companies with projects nearing clinical testing

Newsletter

Don’t miss out—get Ophthalmology Times updates on the latest clinical advancements and expert interviews, straight to your inbox.

Related Videos
(Image credit: Ophthalmology Times) The Residency Report: Study provides new insights into USH2A target end points
Lisa Nijm, MD, says preoperative osmolarity testing can manage patient expectations and improve surgical results at the 2025 ASCRS annual meeting
At the 2025 ASCRS Annual Meeting, Weijie Violet Lin, MD, ABO, shares highlights from a 5-year review of cross-linking complications
Maanasa Indaram, MD, is the medical director of the pediatric ophthalmology and adult strabismus division at University of California San Francisco, and spoke about corneal crosslinking (CXL) at the 2025 ASCRS annual meeting
(Image credit: Ophthalmology Times) ASCRS 2025: Taylor Strange, DO, assesses early visual outcomes with femto-created arcuate incisions in premium IOL cases
(Image credit: Ophthalmology Times) ASCRS 2025: Neda Shamie, MD, shares her early clinical experience with the Unity VCS system
Patricia Buehler, MD, MPH, founder and CEO of Osheru, talks about the Ziplyft device for noninvasive blepharoplasty at the 2025 American Society of Cataract and Refractive Surgeons (ASCRS) annual meeting
(Image credit: Ophthalmology Times) ASCRS 2025: Bonnie An Henderson, MD, on leveraging artificial intelligence in cataract refractive surgery
(Image credit: Ophthalmology Times) ASCRS 2025: Gregory Moloney, FRANZO, FRCSC, on rotational stability
Sheng Lim, MD, FRCOphth, discusses the CONCEPT study, which compared standalone cataract surgery to cataract surgery with ECP, at the 2025 ASCRS Annual Meeting.
© 2025 MJH Life Sciences

All rights reserved.