Higher-order aberrations vary with pupil, optical zone sizes

San Francisco-Use of a larger ablation optical zone size in customized laser-vision correction procedures can minimize surgery- induced increases in higher-order aberrations as well as increases in higher-order aberrations that occur with increasing pupil size, said Scott M. MacRae, MD, at the annual meeting of the American Society of Cataract and Refractive Surgery. Furthermore, the relationship between pupil size and measured higher-order aberrations emphasizes the importance of performing wavefront measurements with an aperture diameter that is at least 6 mm and preferably greater than the mesopic pupil diameter in order to obtain relevant data, Dr. MacRae said.