News

Orlando-In the majority of eyes undergoing primary LASIK, wavefront-adjusted ablation performed with the WaveLight system yields visual outcomes comparable to those achievable with wavefront-guided techniques, said Theo Seiler, MD, PhD, at Back to the Future, the refractive surgery subspecialty day meeting prior to the American Academy of Ophthalmology meeting.

Orlando-CustomCornea wavefront-guided LASIK using the LADARWave aberrometer and the LADARVision4000 excimer laser (Alcon) last October became the first wavefront-guided LASIK system to receive FDA approval for the treatment of myopia. The agency's decision was based on clinical trial data proving that the customized approach delivers superior optical quality compared with conventional LASIK.

Orlando-The CRS-Master (Carl Zeiss Meditec) ablation profile design workstation is a "best of breed" platform for customized ablations because it integrates wavefront, topography, and clinical data for the individual patient while giving the surgeon control in designing the laser treatment, said Dan Z. Reinstein, MD, FRCSC.

Orlando-Six-month results from an FDA clinical trial indicate that customized wavefront-guided LASIK for treatment of myopia with the WavePrint system (VISX) is associated with safe and effective outcomes exceeding FDA targets. The wavefront-guided LASIK is also effective for minimizing increases in higher-order aberrations that can accompany conventional LASIK.

Orlando-Application of wavefront sensing technology has led to the characterization of optical aberrations associated with aging and cataract surgery, and that information is now being applied to develop new pseudo- phakic IOL designs, said Scott M. MacRae, MD.

Orlando-Phototherapeutic keratectomy (PTK) with a broad-beam laser may be a useful treatment for eyes with chronic, visually significant post-LASIK flap microstriae, said Roger F. Steinert, MD, during the refractive surgery subspecialty day meeting prior to the American Academy of Ophthalmology annual meeting.

Here's some good news regarding Medicare reimbursement. American Academy of Ophthalmology (AAO) member William L. Rich III, MD, has been appointed to an influential American Medical Association (AMA) committee on physician reimbursement.

Peapack, NJ-Pharmacia Ophthalmology will begin making its latanoprost ophthalmic solution(Xalatan) available for initial treatment of elevated eye pressure associated with open-angle glaucoma or ocular hypertension.

Salt Lake City-Ofloxacin (Ocuflox, Allergan, Irvine, CA) is more effective for preventing endophthalmitis after cataract surgery compared with ciprofloxacin (Ciloxan, Alcon, Fort Worth, TX), said Randall Olson, MD.

Orlando-Argon laser trabeculoplasty (ALT) can achieve substantial IOP reductions in patients with open-angle glaucoma that is refractory to medical therapy. In addition to efficacy, the cost of the procedure compares favorably with medical treatments, which tend to be substantially more costly over time, according to Karen M. Joos, MD, PhD.

Orlando-Posterior polar cataract is an invitation to capsule rupture and so cataract surgery in these cases necessitates thorough patient counseling, careful preoperative planning, and adaptations in intraoperative technique, said Samuel Masket, MD.

Orlando-Periodic IOP monitoring is mandatory in eyes that have sustained a severe injury because they are at significantly increased risk for developing traumatic glaucoma, said Jess T. Whitson, MD.

Fort Bragg, NC-As a reward for helping a colleague with a difficult postoperative situation, Robert K. Maloney, MD, got thrown out of an airplane, literally.

Salt Lake City-Research from the Moran Eye Center, University of Utah School of Medicine, Salt Lake City, showed that low ocular levels of the antioxidants lutein and zeaxanthin could contribute to age-related macular degeneration (AMD).

Orlando-Advancements in refractive surgery were the talk of Nidek's workshop on customized ablation at the American Academy of Ophthalmology (AAO) annual meeting here last fall. The symposium was intended as a forum for ophthalmologists to gain a better understanding of the technology available to them.

Editor's Note: In this month's column,a panel of experts offers tips on when and how to administer intraocular injectionsof corticosteroid for patients with uveitis.

FDA OKs trials of laser reversal of presbyopia

New York-Research to Prevent Blindness (RPB), a voluntary health organization supporting eye research, awarded 94 grants totalling $9.7 million last year for research into the causes, treatment, and prevention of all blinding diseases.

New York-Pfizer Inc. and Eyetech Pharmaceuticals Inc. will jointly develop and commercialize Eyetech's pegaptanib sodium (Macugen) as a potential treatment for age-related macular degeneration (AMD) and diabetic macular edema (DME).

Indianapolis-Eli Lilly and Co. will delay the submission of its ruboxistaurin for the treatment of diabetic retinopathy and diabetic macular edema (DME) after two clinical trials failed to achieve satisfactory results on disease progression.

Alameda, CA-InSite Vision Inc. and SIFI (Societa Industria Farmaceutica Italiana), a leading Italian pharmaceutical company, will exclusively manufacture, distribute, and promote the OcuGene genetic glaucoma test in Italy.

Ophthalmologists are always looking to broaden their procedure offerings to increase their revenue stream.

A Maryland woman received care instructions for the decorative contact lenses she was buying to match her new dress.

Orlando-A carefully designed comparison study has shown that the fixed combination of dorzolamide-timolol (Cosopt, Merck) is at least as effective as its concomitant components and might provide better trough control in some patients, said Stanley J. Berke, MD, FACS.

Orlando-The incidence of iris hyperpigmentation associated with unoprostone isopropyl ophthalmic solution 0.15% (Rescula, Novartis) was about 1% in two long-term studies, a rate that compares favorably with the incidence of 10% to 20% associated with latanoprost ophthalmic solution (Xalatan, Pharma-cia) in similar patient populations, reported Bernard E. McCarey, PhD.

Bimatoprost 0.03% (Lumigan, Allergan) offers more efficacy than latanoprost 0.005% (Xalatan, Pharmacia) for lowering elevated IOP and is similarly well tolerated, according to the results of a 6-month, multicenter, randomized, double-masked study.

Orlando-Although challenging to set up and conduct, studies that check glaucoma patients' IOP at intervals around the clock for 24 hours or longer provide valuable data about the ability of a medication to lower IOP and reduce fluctuation.

Orlando-Optical coherence tomography (OCT, Carl Zeiss Meditec) offers supe-rior sensitivity and specificity in detect-ing glaucoma and its progression, according to Boston glaucoma specialist Joel S. Schuman, MD.

Orlando-In scanning laser polarimetry (SLP), eye-specific correction of corneal polarization axis and magnitude can be obtained for the quantitative assessmentof the peripapillary retinal nerve fiber lay-er (RNFL) if macular-based strategies are used in eyes free of macular pathology, according to glau-coma specialist David S. Greenfield, MD.

Brimonidine tartrate 0.15% (Alphagan P, Allergan) is a "new and improved" version of brimonidine 0.2% (Alphagan, Allergan). It continues to have an efficacy profile similar to the one ophthalmologists have grown used to with brimonidine 0.2%.