News

Advanced Medical Optics Inc., the Allergan spin-off that went on to become one of the leading publicly traded companies in ophthalmology, will become part of Abbott Laboratories Inc. in a $2.8 billion deal expected to close before the end of the first quarter.

Amid adding partners, opening new offices, and managing unprecedented growth, Mid Atlantic Retina turned to a consulting firm (Advantage Administration Inc.) to develop a strategic plan for the ensuing years.

During their 31st anniversary benefit Jan. 28, the Glaucoma Research Foundation will honor two physicians for their contributions to glaucoma research.

The Vision Care for Kids Act of 2009 was introduced with bipartisan support in the U.S. Senate and House of Representatives, according to prepared statements by The Vision Council and the American Academy of Ophthalmology (AAO), two supporters of the legislation.

Topcon Medical Systems has received FDA clearance for its enhanced 3D optical coherence tomography measurement software (OCT-1000 TrueMap) as an addition to its previously cleared OCT system (3D OCT-1000), according to a prepared statement.

ISTA Pharmaceuticals' new drug application for bepotastine ophthalmic solution (Bepreve) has been accepted for review by the FDA, the company announced in a prepared statement.

Advanced Medical Optics has received FDA approval for a multifocal IOL (Tecnis) for patients with cataracts.

If polled, a majority of optical eye-care professionals (ECPs) likely would report that in addition to their primary pair of eyeglasses, they also own prescription sunwear or quality plano sunwear. Patients also should enjoy the lifestyle and protection that additional sunwear provides. The percentage of prescription sunwear actually dispensed, however, is drastically lower than those worn by ECPs.

Live Eyewear, a privately held corporation that manufactures OveRx (designed to be worn over prescription) sunglasses, was purchased by the company's president, Kieran Hardy.

A scanning laser polarimetry device, which examines the retinal nerve fiber layer, is a beneficial diagnostic tool for glaucoma suspects because it targets the area where the earliest damage from glaucoma is likely to be seen. It also is valuable in monitoring stability or progression in patients with established disease.

Safety data from a multicenter, double-masked, randomized clinical trial comparing the three commercially available prostaglandin analogue IOP-lowering medications containing benzalkonium chloride (BAK) were analyzed to investigate a possible relationship between BAK content and incidence of ocular adverse events. Latanoprost 0.005% (Xalatan, Pfizer), which exposes patients to the highest daily BAK dose, was associated with significantly lower rates of both ocular adverse events and study medication-related adverse events compared with bimatoprost 0.03% (Lumigan, Allergan) and travoprost 0.004% (Travatan, Alcon Laboratories).

The fixed combination of brimonidine and timolol (Combigan, Allergan) provided greater overall patient comfort, and IOP decreased significantly, compared with the fixed combination of dorzolamide and timolol (Cosopt, Merck & Co.) in patients with primary open-angle glaucoma.

Whether opting for an anterior or posterior approach when placing a glaucoma valve, both procedures appear to have similar success in lowering IOP and similar complication profiles, according to the results of a recent study. Nevertheless, some experts believe that the anterior approach may be more advantageous.

Frequency-doubling technology (FDT) has a role as a diagnostic and monitoring instrument for glaucoma, although it may be best used to complement the use of other testing methods, particularly with the newer version of this technology. Studies suggest that the FDT may detect early glaucoma in a different subgroup of patients than other testing devices, and long-term studies will be needed to confirm its effectiveness in detection of progression.

A recent study shows that although the Goldmann applanation tonometer (GAT) is considered to be the standard in detecting eyes with elevated IOP and, therefore, glaucoma, a newer tonometer (Ocular Response Analyzer [ORA], Reichert) appears to be more effective. It also is suggested that glaucoma screening threshold pressure should be lowered from the current 21 mm Hg to 18 mm Hg, which may allow ophthalmologists to more effectively detect glaucoma in their patients.

Due to the frequent coexistence of ocular surface disease and glaucoma in older patients, clinicians should take steps to reduce the potentially damaging effects on the ocular surface of long-term use of glaucoma medication. Reducing the number of medications when possible and choosing those that do not contain the preservative benzalkonium chloride is an approach that may be beneficial in some patients.

Normal-tension glaucoma (NTG) is a form of primary open-angle glaucoma (POAG) in which there is no known history of statistically elevated IOP; however, the definition of an upper limit of normal IOP is arbitrary. POAG is a multifactorial disease process with pressure-dependent and pressure-independent etiologic factors. In NTG, the pressure-independent factors likely play a more substantial role.