
Initial top-line results from a Phase III study of bromfenac ophthalmic solution (Remura, ISTA Pharmaceuticals) indicate that bromfenac was not statistically superior to placebo in treating one sign and one symptom of dry eye disease. ISTA announced this result from the WEST study, the first of two phase III safety and efficacy studies being conducted under a special protocol assessment (SPA) agreed upon with the FDA.