News

Small Incision Lenticule Extraction (SMILE) performed using a femtosecond laser (VisuMax 500 kHz, Carl Zeiss Meditec) is being investigated as a treatment for spherical myopia in a U.S. clinical trial. Positive results were achieved in preliminary analyses of data from 315 eyes.

After watching a muddy high school soccer game, Dr. Rob Kitei and his two daughters were inspired to create a product that could be applied to players’ cleats to prevent mud accumulation. Following acquisition by global brand Mission Athletecare in September 2012, it will be nationally sold this summer.

On the heels of the unanimous rejection by Allergan’s Board of Directors of an unsolicited buyout proposal by Valeant Pharmaceuticals International, Valeant’s top executive intends to issue a financial increase counteroffer in an attempt to salvage the deal.

Results of a commercially available, genetic profiling test for uveal melanoma can be used to determine patients at high risk for metastasis. Understanding of the genetics of the tumor is also being applied to develop targeted therapies that may improve patient survival.

The American Academy of Ophthalmology has developed the Intelligent Research in Sight Registry, the first compressive eye disease outpatient clinical registry in the United States.

The iridociliary sulcus is a hidden region of the eye that provides options for optimizing patient outcomes, particularly in patients with glaucoma.

Pathology in eyes with Marfans syndrome makes cataract surgery challenging and can limit implantation of a toric IOL. Jonathan D. Solomon, MD, describes a Marfans syndrome patient who underwent bilateral surgery with a very successful outcome thanks to the use of a femtosecond laser.

Findings from the HARBOR study on ranibizumab for wet macular degeneration prompted new labeling for a potentially less frequent than monthly dosing, depending on individual responses to treatments.

Ohr Pharmaceuticals has completed the enrollment of its OHR-022 phase II clinical trial evaluating its treatment of we age-related macular degeneration (AMD), Squalamine eye drops.

There are a number of therapeutic options available for managing eyes with recurrent corneal erosion (RCE) syndrome, and a treatment algorithm developed by James J. Reidy, MD, prioritizes their use based on lesion characteristics.

Parion Sciences has received acceptance from the FDA of its Investigational New Drug (IND) application for the company’s treatment for dry eye disease, P-321 ophthalmic solution.

The Association for Research in Vision and Ophthalmology (ARVO) meeting is noted for bringing the latest research and clinical developments to the forefront of clinicians and scientists who venture in the eye-care arena. As with previous meetings, this was prevalent this week in Orlando.

The top three winning descriptions-answering the challenge posed by the Association for Research in Vision and Ophthalmology (ARVO) for members of the eye and vision research community to explain their research to a 12-year-old child in one or two sentences-were announced during the opening ARVO/Alcon Keynote session.

Nonsteroidal anti-inflammatory drugs (NSAIDs) are well recognized as potent agents as they block all downstream prostaglandins, have a long history of safety and efficacy, and fare well in extended-release formulations. Recently, there has been a growing body of evidence showing they have potential in treating cystoid macular edema, said Stephen Kim, MD.

Patients with 2 CFH risk alleles and no ARMS2 risk alleles would be better served by not taking the Age-Related Eye Disease Study (AREDS) formulation, according to Carl C. Awh, MD.

Local delivery of pharmacotherapy to the eye has long been used for anterior segment disease, but various routes for delivery have also been investigated, said Timothy Olsen, MD.

Almost 70% of patients with age-related macular degeneration (AMD) are unaware of their disease until vision loss has occurred, said Gregory R. Jackson, PhD.

The typical eye undergoes 12,000 intraocular pressure (IOP) spikes per hour while awake, and about 3,000 spikes per hour when sleeping, according to J. Crawford Downs.

In roughly 25% of patients, no further treatment was required to maintain mean visual acuity (VA) outcomes achieved at the exit of the RIDE/RISE 3-year core studies evaluating the efficacy of ranibizumab in patients with diabetic macular edema (DME), according to Allen Ho, MD.