
In addition to the primary safety and tolerability endpoints, the study also saw signals of biological response from EXN407

In addition to the primary safety and tolerability endpoints, the study also saw signals of biological response from EXN407

The opportunities and challenges presented by CRISPR manipulation

Since its U.S. launch in September 2023, more than 40,000 avacincaptad pegol intravitreal solution vials have been distributed to physician practices.

According to Alcon, as CMO, Terry Kim, MD, will continue to integrate scientific and clinical priorities across Alcon’s Surgical and Vision Care franchises, with a focus on meeting the needs of patients and eye care practitioners across the globe.

The NOVA clinical trial has found statistical non-inferiority to current clinical standards for sensitivities at individual test locations, glaucoma staging using Medicare definitions, and an exceptionally high correlation of 0.94 in mean deviation.

MCO-010 demonstrated a statistically significant improvement of best-corrected visual acuity (BCVA) at week 52.

The European Commission is expected to make a decision about the application before the end of June.

Stargardt disease is the most common inherited retinal dystrophy (causing blurring or loss of central vision) in both adults and children.

The new cohort will add patients living with IRDs caused by mutations in multiple genes to the already existing cohort of patients with IRDs caused by single gene mutations.

The positive opinion concerns authorization of bevacizumab gamma (ONS-5010/LYTENAVA), a formulation of bevacizumab for treatment of wet age-related macular degeneration (wet AMD).

Alice Epitropoulos, MD, discusses the importance of considering ocular surface health in cataract surgery patients.

A Purdue University researcher is leading a team that is creating patent-pending smart contacts for glaucoma, neovascularization and dry eyes.

In a recent study led by Steven Pittler, PhD, and his team at the University of Alabama Birmingham (UAB), the role of modifier genes in retinitis pigmentosa type 59 (RP59) was meticulously examined.

Results from the trial by Nannodropper show microdrops could reduce waste, cost, and side effects while being as effective as traditional size drops.

The prevalence of AMD features in Republic of Korea Air Force pilots was higher than in other general populations studied.

Multiple symptomatic improvements, as well as tear film break-up time improvements and a reduction in ocular pain, were noted.

The Phase 2 trial tested whether inhibiting microglia with minocycline might help slow GA expansion and its corresponding vision loss.

Indiana University and local public safety officials combine safety and educational efforts.

Laser blended vision is a proven modality for presbyopia treatment, but its principles can be reproduced with EDOF IOLs

Diabetic Retinopathy ranked as the fifth most common cause of blindness among adults aged 50 and older in 2020 according to data from the Global Burden of Disease study. Aude Couturier, MD shares her experience of using advanced imaging technologies to optimize diagnosis and surgical management of her DR patients in our latest Case of the Month.

Lonigutamab is a subcutaneously (SC) delivered humanized IgG1 monoclonal antibody targeting the insulin-like growth factor-1 receptor (IGF-1R).


Office-based surgery could prove to be a viable option for physicians.

Solar retinopathy is caused by prolonged or high intensity exposure of the fovea centralis to light energy. Suspected cases of solar retinopathy may require urgent referral to an ophthalmologist for diagnosis, and to eliminate treatable causes for central visual disturbance.

Proteins common to Alzheimer disease play a significant role in glaucoma

Quantitative and qualitative improvement in IOL design


In court documents in Connecticut Superior Court in Bridgeport, Isidore Sobkowski claims surgeons at the Wilton Surgery Center failed to properly clean their instruments resulting in him contracting a sight-threatening eye infection.

According to the company, NCX 470 is a novel NO-donating bimatoprost eye drop, is currently in Phase 3 clinical development for the lowering of IOP in patients with open-angle glaucoma or ocular hypertension.