Simple solution for presbyopia
A topical product (PresbiDrops, FEPASAET Group) that provides sustained pupil constriction can safely and effectively increase near and distance UCVA in properly selected presbyopic patients.
Take-home message: A topical product (PresbiDrops, FEPASAET Group) that provides sustained pupil constriction can safely and effectively increase near and distance UCVA in properly selected presbyopic patients.
By Cheryl Guttman Krader; Reviewed by Claes Feinbaum, MSc, PhD
Beersheba, Israel-Topical treatment with an investigational proprietary product (PresbiDrops, FEPASAET Group) that combines a parasympathomimetic agent with an NSAID in an oil-based formulation safely and effectively improves near and distance uncorrected visual acuity in properly selected presbyopic patients with low distance prescriptions, according to a study conducted by Claes G. Feinbaum, MSc, PhD.
The efficacy of the pharmacological intervention is explained by changes in pupil size that affect clinical depth of field (DoF) and higher order aberrations (HOAs).
In a series of 81 patients who underwent testing before and 30 to 45 minutes after instillation of 1 or 2 drops of the topical medication, mean pupil size was reduced by an average of 1 mm and was associated with an average 0.9 D increase in DoF.
Both UNVA and UDVA were also significantly improved.
“Excimer laser ablation, femtosecond laser intrastromal ablation, and presbyopia-correcting IOLs can be very effective for improving near vision,” said Dr. Feinbaum, professor and clinical director, research professor of ophthalmology and optometry, Ben Gurion University of the Negev, Beersheba, Israel. “However, visual side effects can occur and may be intolerable for some patients, and reversibility of the cornea-based procedures has not been shown to date.
“Success with the topical pharmacological intervention depends on conducting a complete and careful examination to identify appropriate candidates,” Dr. Feinbaum continued. “For properly chosen presbyopes, however, it is a non-invasive, safe and easy modality for eliminating the use of glasses.”
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