Retinitis pigmentosa may be accompanied by developmental anomalies

The Laurence-Moon/Biedl-Bardet syndrome is an autosomal-recessive disorder with various findings.





A collaborative effort

Moon also collaborated with Laurence on a book entitled A Handy Book of Ophthalmic Surgery that same year, and it was well received by the medical community.

Arthur Biedl (1869-1933), born in Hungary, is best remembered for his pioneering work in endocrinology. His 1910 monograph, Internal Secretions, was so groundbreaking, that Biedl is thought of today as the "father of modern endocrinology." However, in 1922 he described the findings of two sisters who had retinitis pigmentosa, polydactyly, hypogonadism, and obesity. His work was published in the German literature. Two years earlier in 1920, George Lewis Bardet (1885-1970) also had described, in his graduation thesis at the University of Paris, similar findings of two sisters not related to Biedl's discovery.