Article

PRK with MMC as good as LASIK

Wavefront-guided photorefractive keratectomy (PRK) with mitomycin C (MMC) offers very similar results, when correcting compound myopic astigmatism, to wavefront-guided LASIK surgery.

Wavefront-guided photorefractive keratectomy (PRK) with mitomycin C (MMC) offers very similar results, when correcting compound myopic astigmatism, to wavefront-guided LASIK surgery, according to Mauro Campos and colleagues from the Federal University of Sao Paulo, Brazil.

In a prospective, masked, randomized, contralateral eye controlled clinical trial, 84 eyes of 42 patients received customized PRK with MMC in one eye and customized LASIK in the fellow eye. The same postoperative regimens were used in both eyes.

Mean preoperative spherical equivalent (SE) correction was -3.79±1.10 D (PRK) and -3.94±1.18 D (LASIK). At one-year follow-up the percentage of eyes in the PRK group with 0.0, -0.1, -0.2 and -0.3 log MAR uncorrected visual acuity (UCVA) was 13%, 37%, 46% and 4%, respectively and 21%, 54%, 25% and 0%, respectively in the LASIK group. Mean cycloplegic refractive error was +0.48±0.37 D in the PRK group and +0.45±0.54 D in the LASIK group.

The researchers concluded that PRK with MMC is an effective method for correcting compound myopic astigmatism and produces very similar results to wavefront-guided LASIK.

Newsletter

Don’t miss out—get Ophthalmology Times updates on the latest clinical advancements and expert interviews, straight to your inbox.

Related Videos
(Image credit: Ophthalmology Times) NeuroOp Guru: Using OCT to forecast outcomes in ethambutol optic neuropathy
(Image credit: Ophthalmology Times) Inside NYEE’s new refractive solutions center with Kira Manusis, MD
(Image credit: Ophthalmology Times) Dilsher Dhoot, MD, on the evolution of geographic atrophy therapy: where are we now?
(Image credit: Ophthalmology Times Europe) Anat Loewenstein, MD, shares insights on the real-world results of remote retinal imaging
(Image credit: Ophthalmology Times) Two-wavelength autofluorescence for macular xanthophyll carotenoids with Christine Curcio, PhD
(Image credit: Ophthalmology Times) FLIO and the brain: Making the invisible visible with Robert Sergott, MD
(Image credit: Ophthalmology Times) Structure-function correlates using high-res OCT images with Karl Csaky, MD, PhD
(Image credit: Ophthalmology Times) SriniVas Sadda, MD, on high-res OCT of atrophic and precursor lesions in AMD
(Image credit: Ophthalmology Times) Christine Curcio, PhD, shares histology update supporting review software and revised nomenclature for <3 μm OCT
© 2025 MJH Life Sciences

All rights reserved.