Article

Phase III trial uses innovative delivery system to treat DME

Alimera Sciences Inc. and Control Delivery Systems Inc. (CDS) began a phase III clinical trial to study patients with diabetic macular edema (DME) treated using the Medidur implant to deliver fluocinolone acetonide.

The masked, randomized, multicenter study will follow 900 patients in the United States and Europe for 36 months. The Medidur implant, injected through a needle during an in-office procedure, is expected to provide sustained delivery of fluocinolone acetonide to the back of the eye for up to 3 years, according to Alimera Sciences.

"Advanced therapies require innovative methods of delivery, and Medidur fits that model," said Dan Myers, president and chief executive officer of Alimera Sciences, Alpharetta, GA. "The Alimera Sciences team is delighted to reach this critical product development milestone with CDS at such a stage of our company's progression. We anticipate that Medidur technology will allow eye-care professionals to provide their DME patients with an effective and long-lasting therapeutic treatment."

Newsletter

Don’t miss out—get Ophthalmology Times updates on the latest clinical advancements and expert interviews, straight to your inbox.

Related Videos
(Image credit: Ophthalmology Times) NeuroOp Guru: Using OCT to forecast outcomes in ethambutol optic neuropathy
(Image credit: Ophthalmology Times) Inside NYEE’s new refractive solutions center with Kira Manusis, MD
(Image credit: Ophthalmology Times) Dilsher Dhoot, MD, on the evolution of geographic atrophy therapy: where are we now?
(Image credit: Ophthalmology Times Europe) Anat Loewenstein, MD, shares insights on the real-world results of remote retinal imaging
(Image credit: Ophthalmology Times) Two-wavelength autofluorescence for macular xanthophyll carotenoids with Christine Curcio, PhD
(Image credit: Ophthalmology Times) FLIO and the brain: Making the invisible visible with Robert Sergott, MD
(Image credit: Ophthalmology Times) Structure-function correlates using high-res OCT images with Karl Csaky, MD, PhD
(Image credit: Ophthalmology Times) SriniVas Sadda, MD, on high-res OCT of atrophic and precursor lesions in AMD
(Image credit: Ophthalmology Times) Christine Curcio, PhD, shares histology update supporting review software and revised nomenclature for <3 μm OCT
© 2025 MJH Life Sciences

All rights reserved.