Low-dose intravitreal triamcinolone lowers incidence of steroid-induced glaucoma

Jeffrey D. Benner, MD, clinical professor of ophthalmology at the University of Maryland School of Medicine and a partner in the Retina Consultants of Delmarva, decided to explore the lower dose of IVTA after one of his patients developed severe glaucoma following an intravitreal injection of 4 mg of triamcinolone acetonide.

Injecting triamcinolone acetonide into the vitreous has emerged as a promising treatment for diabetic macular edema and other conditions that cause macular edema. The most frequent complication associated with IVTA has been elevation of the IOP. The incidence of steroid-induced elevation of the IOP after IVTA as reported in the literature ranges from a low of 25% (4 mg)¹ to a high of 52% (25 mg).²