News

Nice, France-Although the incidence of epithelial ingrowth as a complication of LASIK is declining, considerable uncertainty remains over when to intervene, according to Arun C. Gulani, MD. In response, Dr. Gulani has devised a grading system to help surgeons answer that question by placing values on the density of the epithelial ingrowth

Therapies for retinal diseases that re-mained untreatable for decades are seeing major advances. So much so that Jason Slakter, MD, clinical professor of ophthalmology, New York University School of Medicine, and surgeon director, Manhattan Eye, Ear, & Throat Hospital, New York, has proclaimed the first years of the new mil-lennium as the "Decade of the Macula."

Editor's Note: HIV/AIDS continues to be a major health problem, not only in the developing world, but in North America and Europe as well. Although the incidence of ocular complications of HIV/AIDS has decreased dramatically since the introduction of highly active anti-retroviral therapy (HAART), the prevalence of HIV positivity continues toincrease, particularly among heterosexual women and minorities.

Publication of results from the Ocular Hypertension Treatment Study (OHTS) and the Early Manifest Glaucoma Trial (EMGT) represents two of the most notable events occurring in the field of glaucoma in 2002, but the year is also marked by a number of other significant developments with the potential to influence patient evaluation and management.

Editor's Note: This is the final story in a three-part series covering a forum on "Ethnicity and Glaucoma" at Johns Hopkins University to commemorate the 20th anniversary of the Baltimore Eye Survey.

Orlando-A task force composed of 30 leading ophthalmologists and retinal specialists is recommending the use of a new, five-level classification system for distinguishing degrees of diabetic retinopathy. The results of this effort were highlighted at a news conference held during the American Academy of Ophthalmology (AAO) annual meeting in Orlando.

Carlsbad, CA-The Pulsion FS femtosecond laser keratome (IntraLase Corp., Irvine, CA) appears to be an important new instrument for use in the treatment of lamellar keratoplasty, among others, according to Lee T. Nordan, MD, who described his preliminary results.

Nice, France-Custom ablation is a useful technique for eyes that have not been treated with a refractive procedure. But this approach can also be used to improve the quality of vision in previously treated eyes that exhibit symptoms such as glare, halos, night vision difficulties, or monocular diplopia, according to Omar J. Hakim, MD, who spoke during the XX Congress of the European Society of Cataract and Refractive Surgeons (ESCRS).

Charleston, SC-When prescribing brimonidine 0.2% b.i.d. as monotherapy for ocular hypertension or primary open-angle glaucoma, physicians should make sure that the drug maintains its effectiveness in the late afternoon and may want to add a third drop to the daily dosage, said William C. Stewart, MD.

Green Bay, WI-The recently introduced miniature glaucoma shunt (Ex-Press) is an exciting modality with a lot of potential, but this new IOP-lowering treatment still requires further study to define its long-term efficacy and place in the armamentarium of glaucoma management options, said James E. Memmen, MD.

Los Angeles-A randomized, controlled trial comparing the combination therapy dorzolamide-timolol (Cosopt, Merck) with concomitant administration of 2% dorzolamide (Trusopt, Merck) and 0.5% timolol showed that the IOP lowering is equally effective if the drugs are given either in combination or individually.

Houston-In patients with primary open-angle glaucoma (POAG) or ocular hypertension (OH), once-daily treatment with fixed-combination latanoprost/timolol (Xalacom, Pharmacia, Peapack, NJ) is well tolerated and lowers IOP more effectively than twice-daily dorzolamide/timolol (Cosopt, Merck), according to a recent multicenter U.S. study.

Baltimore-Latanoprost 0.005% (Xalatan, Pharmacia) taken once daily is more effective in lowering IOP than unoprostone 0.15% (Rescula, Novartis) taken twice daily, according to a recent multicenter study, reported Henry D. Jampel, MD, MHS.

Houston-Once-daily bimatoprost 0.03% (Lumigan, Allergan) is a highly effective, safe, and well-accepted IOP-lowering medication across the di-verse population of patients encountered in daily practice, according to the results of a large-scale, com-munity-based, pro-spective, open-label study.

Tucson, AZ-Topical beta-blockers have been a mainstay of ongoing treatment for glaucoma for more than 20 years, but a new study adds to the evidence that they may not be the best option for long-term control of IOP for elderly patients.

Editor's note: This is the second story in a three-part series covering a forum on "Ethnicity and Glaucoma" at Johns Hopkins University to commemorate the 20th anniversary of the Baltimore Eye Study. The meeting was sponsored by Johns Hopkins University School of Medicine and Ophthalmology Times and supported through an unrestricted educational grant from Alcon Laboratories Inc.

La Jolla, CA-Results from murine studies indicate that a population of adult bone marrow-derived hematopoietic stem cells injected intravitreally will selectively target activated astrocytes, become incorporated into blood vessels, and promote or inhibit retinal angiogenesis, reported Martin Friedlander, MD, PhD.

Nice, France-With the introduction of new implantation devices, the AcrySof IOL (Alcon, Fort Worth, TX) is now much easier to manipulate compared with previously. Takayuki Akahoshi, MD, director of ophthalmology, Mitsui Memorial Hospital, Tokyo, Japan, introduced the new implantation devices here at the XX Congress of the European Society of Cataract and Refractive Surgeons.

The new LASIK Certification Program developed by the American Board of Eye Surgery (ABES) is seen as being a long time coming and an important step in the right direction for the entire field of medicine.