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Washington, DC-As a 31-year-old doctor fresh out of residency, Arnall Patz, MD, suggested a connection between high levels of oxygen and premature infants' blindness, and the medical community reacted with near hostility.

The FDA has approved a new drug application by ISTA Pharmaceuticals for the once-daily liquid formulation of timolol 0.5% as a therapy for glaucoma.

Fort Lauderdale, FL-Supplemental inspired oxygen may decrease macular thickening due to diabetic macular edema (DME), according to the results of a pilot study presented by Quan Dong Nguyen, MD, MSc, at the annual meeting of the Association for Research in Vision and Ophthalmology.

Washington, DC-Pulsed treatment with the 532-nm, diode-pumped, frequency doubled, solid-state green laser (OcuLight GLx, Iridex) appears to be a safe and effective method for closing the retinal arteriolar connections that feed early stage lesions of retinal angiomatous proliferation (RAP), said Robert P. Murphy, MD.

Iowa City, IA-The development of gene-directed therapy for common genetic ocular diseases that will be deployable on a population scale rests on coordinated research involving a series of steps. However, judging from progress made so far, such modalities might become clinically available soon, said Edwin M. Stone, MD, PhD.

Miami-Treatment with small interfering RNA (siRNA) directed against vascular endothelial growth factor (VEGF) is showing promise as a new therapy for choroidal neovascularization (CNV), according to Michael J. Tolentino, MD, who spoke at Angiogenesis 2004.

Fort Lauderdale, FL-A series of studies is evaluating the angiostatic cortisene compound anecortave acetate (Retaane, Alcon Laboratories) as both a prophylactic and therapeutic intervention for choroidal neovascularization (CNV) in eyes with age-related macular degeneration (AMD), said Jason S. Slakter, MD, at the annual meeting of the Association for Research in Vision and Ophthalmology.