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As part of Ophthalmology Times’ coverage of the 2014 meeting of the Association for Research in Vision and Ophthalmology, Group Content Director Mark L. Dlugoss writes this blog with his observations of the meeting.

Regeneron Pharmaceuticals and Avalanche Biotechnologies announced a collaboration to discover, develop, and commercialize novel gene therapy products for the treatment of ophthalmologic diseases.

Retinal angiomatous proliferation (RAP) lesions, treatment with ranibizumab, the absence of subretinal fluid, and the absence of subretinal pigment epithelium fluid (RPE) were associated with fewer injections for neovascular age-related macular degeneration (AMD) among participants from the Comparison of AMD Treatments Trials (CATT), said Daniel F. Martin, MD.

Selective laser trabeculoplasty (SLT) without the use of a gonioscopy lens was performed successfully and still decreased IOP over 6 months, said Michael Belkin, MD.

LENSAR and TrueVision 3D Surgical have made a global co-development and distribution agreement that integrates TruVision’s overlay and nomogram-the TrueGuide system-into LENSAR’s laser system’s advanced technology suite.

A feature-rich FLEX visual acuity (VA) app for ophthalmology, optometry, clinical trials, and other medical uses has been released on Apple iTunes for retina display iPad devices as an add-in to Konan Medical’s Chart2020 Duo app.

Contemporary phakic IOLs are safe and effective for treating high ametropias. Further developments are expected to address some of the remaining needs, but the problem of complications due to interference with surrounding ocular tissues may never be overcome.

Based on unknown preoperative anatomic considerations, efficacy, and safety data, phacotrabeculectomy may be a better option than phacoemulsification alone or combined with a microincision glaucoma surgical procedure in eyes with advanced glaucoma needing cataract surgery and low IOP.

Eye-care professionals can employ a variety of techniques and diagnostic technologies to identify infection, eliminate it, and improve outcomes for their patients.

The looming promise of a well-tolerated and extremely effective oral agent to eradicate HCV infection is exciting, as it offers the possibility of eliminating this disease as a significant public health problem, as well as the albeit uncommon ophthalmic manifestations.

This new session will explore the role of women in ARVO’s leadership in the context of some of the critical issues facing women in the scientific, medical, and academic workforce today.

Each year, ARVO presents several annual achievement awards, and the recipients are invited to give lectures. Here are this year’s winners.

As a vital part of securing public support for vision research, the Association for Research in Vision and Ophthalmology (ARVO) posed a challenge to members of the eye and vision research community. Can you explain your research to a 12-year-old child in one or two sentences?

CheckedUp, a mobile health platform being tested at a number of sites nationwide, is designed to supplement cataract patients’ office visits by providing ongoing customized education and communication throughout the care process.

In a multicenter phase II study of cataract surgery patients, recipients of a dexamethasone-releasing punctum plug (Ocular Therapeutix) were significantly more likely than their vehicle-treated counterparts to be free of pain and anterior chamber cells at various postoperative follow-up visits.

The implementation of an electronic health record system at the Wilmer Eye Institute has shed light on its use, adoption, satisfaction, and productivity.

Collagen crosslinking (CXL) is currently used to treat keratoconus, pellucid marginal degeneration, and post-LASIK ectasia, although it has not yet received FDA approval. Thomas John, MD, discussed the potential of the technology to treat corneal infections.

Collagen crosslinking (CXL) provides good results in young patients with keratoconus, but the key to success in these young patients is rapid treatment upon presentation without waiting for disease progression, said Paolo Vinciguerra, MD.

Combination therapy of collage crosslinking (CXL) and intacs (Addition Technology, Inc.) may be a good treatment for mild-to-moderate keratoconus, according to David Rootman, MD.

The benefit-to-risk ratio of phakic IOLs is well-balanced, and while there is a risk of decreased endothelial cell counts in some eyes with certain phakic IOLs, the optical quality achieved is very good, said Thomas Kohnen, MD, PhD.

Femtosecond laser-assisted cataract surgery in children with cataract was uneventful, safe, and resulted in good outcomes, despite being an off-label use of the technology, said Burkhard Dick, MD.

Femtosecond laser lenticule extraction (small-incision lenticule extraction) performed to treat spherical myopia resulted in rapid and significant improvements in visual acuity. John Doane, MD, reported the preliminary data from the U.S. clinical trial.