Ilya Petrou, MD


Glaucoma: Hyperemia a common cause for medication changes

Hyperemia is one of the main reasons why patients with glaucoma do not adhere to or persist with their topical therapeutic regimen. Patients end up switching to another possibly more tolerable medication, and the changing of medications has significant financial implications. Latanoprost has the lowest incidence of hyperemia among the prostaglandin analogs. Patient adherence is crucial in a chronic progressive disease such as glaucoma, where non-adherence can lead to visual loss and decline in quality of life, creating societal health and economic burdens.

Brimonidine/timolol controls IOP in clinical setting

Brimonidine 0.2%/timolol 0.5% fixed-combination ophthalmic solution effectively lowers and controls IOP and is likely to be associated with increased patient adherence to therapy and decreased unwanted side effects such as ocular irritation, according to one ophthalmologist.

Low IOP is measured with great accuracy using non-contact applanation tonometer

A non-contact applanation tonometer (Ocular Response Analyzer, Reichert) appears to be more effective than the Goldmann applanation tonometer (GAT) in assessing very low and negative IOP values using the non-contact applanation tonometer's corneal-compensated IOP (IOPcc) parameter. The GAT may be the long-accepted gold standard, but the more accurate assessment of IOP using the non-contact applanation tonometer challenges this gold standard and raises questions as to which of the two techniques is optimal in measuring IOP.

Oral fenretinide may slow, halt geographic atrophy in those with age-related macular degeneration

August 01, 2009

Oral fenretinide given once daily may slow the progression of geographic atrophy in patients with age-related macular degeneration, according to an interim analysis.