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Allergan is working on plans of its own to give investors "most of what they want" instead of the $53 billion hostile bid from Valeant Pharmaceuticals International and top Allergan shareholder Pershing Square, according to the company.

When consulting with patients who present with decreased vision due to cataracts, ophthalmologists need to remember their role as physicians first, suggest the authors. The primary goal of the office visit is to address the complaint and the solution in entirety before moving into outcomes.

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Common imaging techniques-such as optical coherence tomography and ultrasound biomicroscopy-can be enlisted to help with research into retinal diseases when used to examine postmortem eyes, suggest findings from a collaborative research program.

The open-label extension RIDE and RISE phase III studies of ranibizumab (Lucentis, Genentech) indicated that the beneficial results of the drug for treating diabetic macular edema were maintained over the long-term with less than monthly follow-up or injection treatment.

The first results from a phase I trial of gene therapy for exudative age-related macular degeneration using a subretinal injection suggest that the treatment is safe and well tolerated even in the elderly population and may eliminate the need for frequent reinjection with anti-vascular endothelial growth factor agents.

Nicox S.A. has signed an agreement to acquire all of the outstanding equity of Aciex Therapeutics, a private, U.S.-based, ophthalmic development pharmaceutical company with a pipeline of therapeutics addressing the ophthalmic market, including allergy and inflammation.

Ohr Pharmaceutical has announced positive top-line interim results for its double-masked, placebo-controlled phase II clinical trial of Squalamine eye drops in patients with wet age-related macular degeneration (AMD).

Aerie Pharmaceuticals has reported successful results for a phase IIb trial for its IOP-lowering therapy-once-daily, quadruple-action Roclatan, a combination of Aerie’s triple-action Rhopressa with latanoprost.

Alimera Sciences' sustained-release intravitreal implant (Iluvien)-its treatment of chronic macular edema-has received a positive outcome of the Repeat-Use Procedure with the Medicines and Healthcare products Regulatory Agency of the United Kingdom serving as the Reference Member State.

A healthy, stable tear film is essential for high quality visual function and stable interblink vision. If patients have dry eye disease, it must be successfully resolved before corneal refractive surgery takes place. Similarly, patients who do not have preoperative dry eye but are at high risk of developing the disease postoperatively also need special attention.

The 1-year results of the inject-and-extend Lucentis Compared to Avastin Study (Lucas) for exudative age-related macular degeneration (AMD) indicated that the two drugs have equivalent effectiveness, said Karina Berg, MD.

The FDA has issued a marketing clearance for Bausch + Lomb’s presbyopia treatment, Biotrue ONEday (nesofilcon A) soft (hydrophilic) daily disposable multifocal contact lenses.

The FDA has approved Allergan’s dexamethasone intravitreal implant (Ozurdex), as a treatment option for diabetic macular edema (DME) in adult patients who have an artificial lens implant or who are scheduled for cataract surgery.

The Federal Trade Commission (FTC) is requiring Akorn Enterprises’ subsidiary Hi-Tech Pharmacal to sell the marketing rights for five generic drugs to Watson Laboratories to settle federal charges that Akorn’s acquisition of Hi-Tech was anticompetitive.