News

Allergan has fired back in response to Pershing Square Capital Management’s announcement that it will hold a special meeting with Allergan shareholders, where it will ask to oust six of Allergan’s nine directors in an attempt to pass Valeant Pharmaceuticals International’s re-revised unsolicited takeover proposal of the company.

Alcon Laboratories’ Dave Sattler, FAAO, will retire Aug. 2 after 28 years of service.

The FDA has approved Omeros’ phenylephrine and kertorolac injection 1%/0.3% (Omidria) for use during cataract surgery or IOL replacement (ILR) to maintain pupil size by preventing intraoperative miosis and to reduce postoperative pain.

Allergan has publicly acknowledged that Valeant Pharmaceuticals International, along with Pershing Square Capital Management, have made a second revised, unsolicited proposal to acquire all of the outstanding shares of the company.

Although patients undergoing thin-flap LASIK performed with modern femtosecond and excimer lasers can expect excellent vision on the day after surgery, faster visual recovery might enhance the procedure’s appeal, according to Daniel S. Durrie, MD.

The Affordable Care Act continues to change and ophthalmology must change in order to adapt.

A phase III clinical trial of lifitegrast 5% ophthalmic solution for treatment of dry eye showed treatment benefit across all symptom endpoints.

The Infant Aphakia Treatment Study evaluated outcomes after unilateral cataract surgery during early infancy in children randomly assigned to primary aphakic correction with an IOL or contact lens. Visual acuity results and clinical findings during follow-up through age 5 were recently published.

A thermal pulsation system can safely and effectively treat meibomian gland obstructions in both the upper and lower eyelids simultaneously during an in-office procedure that takes only 12 minutes.

A new hypochlorous acid lid cleanser is a safe and effective option for cleaning the lids, lashes, and periocular skin of debris and microorganisms.

A new test for the diagnosis of Sjögren’s syndrome may change ophthalmic practices’ approach to the management of dry eye.

Use of an inverted side cut when performing LASIK speeds recovery of corneal sensation.

CO2 laser-assisted sclerectomy surgery reduces elevated IOP by thinning the sclera of the eye while leaving an intact membrane.

Use of a femtosecond laser for cataract surgery is accompanied by increases in cost and time. However, available information on these and other issues support the procedure.

The "Glaucoma 360 Annual Gala" raises money for GRF research and education. The gala includes a reception, silent and lives auctions, dinner, entertainment, and awards. For a glimpse of the evening's festivities, view the slide show.

John Sheppard, MD, highlights results of a phase III randomized, double-masked, placebo-controlled trial of lifitegrast in dry eye patients previously on artificial tears. He presented these results, a subset analysis of the OPUS-1 phase III trial, at the 2013 meeting of the American Society of Cataract and Refractive Surgery.

Early treatment of pediatric cataracts is crucial, with proper consideration being given to age and the type of postoperative correction to be used.

The advent of 24-hour IOP monitoring will transform the care of patients with glaucoma and usher in a new era of personalizing IOP.24-hour IOP monitoring set to revolutionize glaucoma research and clinical care.

Increased patients and patient access, new payment models, and the rise of comparative effectiveness research top the list of challenges that ophthalmologists will face in the future, according to William L. Rich, III, MD, FACS.

“New Horizons in Glaucoma Drug Delivery” session reviewed nine development programs. Some companies are focusing on micro- and nano-scale particles, others on gels and solid drug depots. All aim for controlled, steady state delivery over specific time periods to enhance drug delivery to the target tissue and improve therapeutic outcomes.

Big Pharma is on the hunt for new glaucoma drugs. The pace of therapeutic development is picking up. The “New Horizons in Glaucoma Pharmaceuticals” highlighted four companies with strong new drug candidates.

Listen as Gil Kliman, MD, managing director of InterWest Partners, interviews Richard Lindstrom, MD, in a one-on-interview at the 2014 Glaucoma 360 meeting. Dr. Lindstrom recalls how he was primed as a boy for the construction business by his father, but decided to go to medical school. The decision catapulted Dr. Lindstrom’s career as ophthalmologist, surgeon, and product innovator.

Intraocular pressure (IOP) monitoring is based on fiction. Clinicians typically measure IOP over a single visit and extrapolate the value to the patient’s overall condition and the degree of control over their IOP. “New Horizons in IOP Monitoring and Digital Health” session showcased six companies trying to turn the IOP challenge into commercial success.

The search for glaucoma biomarkers is in high gear. Funded by Catalyst for a Cure, the research program has already produced new biomarker candidates and novel techniques that promise to advance research in glaucoma. Research is focusing on ways to diagnose glaucoma early and detect the specific, minute changes that could allow researchers to reduce vision loss.

The next decade will be a period of remarkable research discoveries for glaucoma and their translation into enhanced patient care, according to Robert N. Weinreb, MD. Glaucoma research will transform and will dramatically change the clinical practice. Dr. Weinreb discussed improvements in risk-prediction and risk-modification strategies, increased knowledge of glaucoma pathophysiology, the advent of 24-hour IOP monitoring, and advanced technologies for structural and functional imaging.

Micro-invasive glaucoma surgery (MIGS) devices for glaucoma were big news in 2013. In 2014, MIGS devices represent big dollars. Steven Vold, MD, moderated the panel on the “New Horizons in Glaucoma Devices” at the 2014 Glaucoma 360 meeting.

The availability of technologies for ambulatory IOP measurement will usher in a new era in glaucoma patient management. L. Jay Katz, MD, said the technologies will provide better understanding of IOP and patient adherence to topical medications and to make more timely adjustments in therapy while reducing the number of office visits.

Clinical registries can lead to better outcomes, better science, and better drug and device surveillance, reports William L. Rich, III, MD, FACS. Registry measures performance, both process measures in the office, and surgical interventions, and provides a forum to compare them and improve.

The glaucoma pharmaceutical sector alone is set to grow from $4 billion in 2013 to $5 billion by 2018. Innovation in glaucoma diagnosis and treatment is alive, well–and profitable. That was the upbeat report from Emmett Cunningham, Jr., MD, PhD, MPH, ophthalmologist and partner with venture capital firm Clarus Ventures, LLC.

Ruth D. Williams, MD, a glaucoma consultant and partner at the Wheaton Eye Clinic, Naperville, IL, explored the possible effects and correlations in concomitant treatment of hypertension and glaucoma.