Second-harmonic signaling used to study corneal structure, function

Second-harmonic signaling with the femtosecond laser (IntraLase, Advanced Medical Optics) can be used to probe corneal structure and function. In combination with laser-induced optical breakdown, it also can help create three-dimensional measures of elasticity as well as provide details on the biomechanical properties of the eye, according to James V. Jester, PhD, professor of ophthalmology, University of California, Irvine.