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Second-harmonic signaling with the femtosecond laser (IntraLase, Advanced Medical Optics) can be used to probe corneal structure and function. In combination with laser-induced optical breakdown, it also can help create three-dimensional measures of elasticity as well as provide details on the biomechanical properties of the eye, according to James V. Jester, PhD, professor of ophthalmology, University of California, Irvine.
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