Article

Options for surgical management of IFIS are multiple

Several options are available to cataract surgeons to manage anticipated IFIS. In the multicenter prospective trial, surgeons could use a mechanical restraining device (iris expansion ring or iris retractors) to enlarge the pupil and keep the iris from prolapsing, viscodilation with Healon 5 (Advanced Medical Optics), or pharmacologic intervention with atropine administered three times daily beginning 2 days before surgery.

Several options are available to cataract surgeons to manage anticipated IFIS. In the multicenter prospective trial, surgeons could use a mechanical restraining device (iris expansion ring or iris retractors) to enlarge the pupil and keep the iris from prolapsing, viscodilation with Healon 5 (Advanced Medical Optics), or pharmacologic intervention with atropine administered three times daily beginning 2 days before surgery.

Viscodilation should be combined with low-flow, low-vacuum surgery and can also be performed using DisCoVisc (Alcon Laboratories) as the ophthalmic viscosurgical device. Other techniques that have been reported successful include intraoperative mydriatic treatment with epinephrine injected under the iris, as described by Joel Saugar, MD, or with intraocular phenylephrine, as reported by Richard Packard, MD.

The prospective, multicenter study undertaken to characterize the safety of cataract surgery in patients taking tamsulosin using the various techniques was not intended to establish the superiority of any one strategy. As observed by Samuel Masket, MD, the clinical reality is that the various techniques should not be considered mutually exclusive, but rather as complementary.

Dr. Masket initiated the concept of using preoperative atropine, and he reported that he has accumulated a series of 20 patients at risk for IFIS in whom he has used it combined with intraocular epinephrine. In 19 eyes, the case proceeded uneventfully, while it was necessary also to place iris hooks to achieve adequate dilation in one patient who had a very small pupil.

Newsletter

Don’t miss out—get Ophthalmology Times updates on the latest clinical advancements and expert interviews, straight to your inbox.

Related Videos
(Image credit: Ophthalmology Times) From MIGS to gene therapy: Inder Paul Singh, MD, celebrates the past and future of glaucoma care
(Image credit: Ophthalmology Times) NeuroOp Guru: Using OCT to forecast outcomes in ethambutol optic neuropathy
(Image credit: Ophthalmology Times) Inside NYEE’s new refractive solutions center with Kira Manusis, MD
(Image credit: Ophthalmology Times) Dilsher Dhoot, MD, on the evolution of geographic atrophy therapy: where are we now?
(Image credit: Ophthalmology Times Europe) Anat Loewenstein, MD, shares insights on the real-world results of remote retinal imaging
(Image credit: Ophthalmology Times) Two-wavelength autofluorescence for macular xanthophyll carotenoids with Christine Curcio, PhD
(Image credit: Ophthalmology Times) FLIO and the brain: Making the invisible visible with Robert Sergott, MD
(Image credit: Ophthalmology Times) Structure-function correlates using high-res OCT images with Karl Csaky, MD, PhD
(Image credit: Ophthalmology Times) SriniVas Sadda, MD, on high-res OCT of atrophic and precursor lesions in AMD
(Image credit: Ophthalmology Times) Christine Curcio, PhD, shares histology update supporting review software and revised nomenclature for <3 μm OCT
© 2025 MJH Life Sciences

All rights reserved.