Jules Stein Eye Institute milestones in research

November 1, 2006

Below is a partial list of the contributions made by researchers at the Jules Stein Eye Institute and the University of California, Los Angeles, over the past 40 years.

Below is a partial list of the contributions made by researchers at the Jules Stein Eye Institute and the University of California, Los Angeles, over the past 40 years.

Late 1960s-Demonstrated the progress of photoreceptor renewal in the retina.

Early 1970s-Investigated the peripheral retina, leading to improved treatments for retinal detachment.

1970s-Pioneered many plastic surgery techniques, including the Madame Butterfly procedure for reconstruction of the lower eyelid, the transcaruncular orbitotomy, and the deep lateral orbital decompression.

1980s-Identified extended contact-lens wear as a risk factor for corneal infections.

1982-Wrote the first paper describing how AIDS reveals itself in the eye.

1984-Created new muscle transposition surgical procedures for the treatment of strabismus.

1990-Pinpointed the role of the orbital pulley system in ocular motility and strabismus.

1992-Originated the use of the antiseptic povidone iodide to prevent postoperative infections and neonatal ophthalmia.

1990s-Developed special magnetic resonance imaging techniques to image eye muscles for more precise diagnosis of complicated cases.

Late 1990s-Recognized the role of stress proteins in the protection of retinal ganglion cell death from glaucoma.

Late 1990s-Created a knockout mouse model for Stargardt's syndrome that scientists are using to develop genetic and drug treatments for retinal disease.

1999-Participated in early clinical trials of anti-vascular endothelial growth factor therapy, which revolutionized therapy for age-related macular degeneration and diabetic retinopathy.

2003-Pinpointed the importance of long-term IOP fluctuation as a risk factor for progressive glaucoma.

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