ASCRS Live: 36-month outcomes for the Juvene modular intraocular lens

Sam Garg, MD, discussed his paper on the 36-month outcomes for the Juvene modular intraocular lens at the 2023 ASCRS annual meeting in San Diego.

Video transcript

Editor’s note: Transcript lightly edited for clarity.

Sam Garg, MD:

Hi, my name is Sam Garg from the University of California, Irvine, where I'm a cornea, cataract, and refractive surgeon there. I'm excited to talk today from ASCRS 2023 in San Diego about the paper I presented yesterday on the 36-month outcomes for the Juvene modular intraocular lens. This is a lens made by a company, LensGen, and it's a modular IOL that has two parts. It has a base lens that fills the capsular bag, and then a fluid-filled optic that you tap into that base lens. The fluid-filled lens has a shape change on the anterior aspect of it when you get accommodative amplitude.

We've published in the past, and presented here in the past, our 12-month and 24-month data. Yesterday, I was able to present the 36-month data. What we found is excellent...in patients that were implanted monocularly...excellent distance, intermediate, and near vision. And then as expected, in the binocular patients at 36 months we showed excellent 20/20 distance; 20/25 intermediate, and very functional near at J3 or better for the bilateral patients.

What was most exciting about this paper was that we were able to see how the lens does over time. What we found was that the effect... First of all, the range of vision, the quality of vision, and the amplitude of accommodation was consistent from 1 to 2 to 3 years. We're seeing that this lens is maintaining its effect over time.

The last bit of data that I presented was the endothelial cell health on these patients out to 3 years. We found that the endothelial cell loss was comparable to standard cataract surgery. All in all, we're hoping this will be a very nice lens for patients where we're going to be able to balance both quality of vision and range of vision without having to worry about dysphotopsia and loss of contrast.