TTT trial to test potential treatment for wet AMD
May 1st 2003Mountain View, CA-IRIDEX Corp. has completed enrollment in a clinical trial for its TTT4CNV, to determine whether trans-pupillary thermotherapy (TTT) laser treatment can reduce the risk of vision loss for patients with occult wet age-related macular degeneration (AMD).
ISTA to try again after FDA panel rejects Vitrase
May 1st 2003Irvine, CA-ISTA Pharmaceuticals is regrouping after an FDA advisory committee said the company's tests of ovine hyal-uronidase (Vitrase) failed to demonstrate sufficient statistical evidence to support its efficacy in treating vitreous hemorrhage.
Allergan begins launch of cyclosporine
May 1st 2003Irvine, CA-In early April, cyclosporine ophthalmic emulsion 0.05% (Restasis, Allergan) became commercially available for the treatment of eye inflammation associated with keratoconjunctivitis sicca. The introduction of the product marks the first therapeutic option for people with dry eye by not only providing temporary relief of dry eye, but also treating the associated ocular inflammation, according to the company.
Anti-VEGF treatment shows promise in preliminary trials
April 15th 2003Boston-Multiple intravitreal injections of rhuFab V2 (Genentech Inc., San Francisco) are well-tolerated and appear to have favorable biologic activity for the treatment of exudative age-related macular degeneration (AMD), said Jeffrey S. Heier, MD, of Ophthalmic Consultants of Boston and the Center for Eye Research, principal investigator for that trial.
OCT useful for detecting vitreofoveal traction, thickness
April 15th 2003Royal Oak, MI-Optical coherence tomography (OCT) may be more sensitive than fluorescein angiography in detecting vitreofoveal traction and differences in thickness in the different areas of the macula in patients with persistent diabetic macular edema (DME). While fluorescein angiography remains the standard in imaging, Cynthia Carvalho-Recchia, MD, suggested an adjunctive role for OCT in patients with DME.
Breakthrough seen in canine Leber's congenital amaurosis
April 15th 2003Philadelphia-Gene therapy has successfully restored the visual function of blind dogs with a rare congenital retinal disease, according to early research results. This breakthrough holds implications for the treat- ment of several human retinal degenerative diseases within the next several years.
PRK okay for U.S. Army Special Forces using night vision goggles, study concludes
April 15th 2003Washington, DC-PRK causes no loss of visual resolution and, in fact, improves uncorrected visual acuity (UCVA) and visual resolution during use of night vision goggles under a range of night sky conditions.
ARVO celebrates 75 years of research, vision
April 15th 2003Fort Lauderdale, FL-The Association for Research in Vision and Ophthalmology (ARVO) turns 75 years this year. To commemorate this major milestone, several special events are planned during the annual meeting from May 4 to 8 in Fort Lauderdale, FL.
Microbursts of ultrasound increase safety, efficiency
April 15th 2003Orlando-WhiteStar, a power control upgrade for the Sovereign system (AMO, Santa Ana, CA), maximizes the efficiency and safety of phacoemulsification for cataracts of any hardness, according to speakers at an American Academy of Ophthalmology an-nual meeting breakfast symposium sponsored by AMO.
IOL edge design directly affects ability to see at night
April 15th 2003Salt Lake City-Dysphotopsias, the unwant-ed optical images seen at night, pose an annoying and sometimes debilitating effect for cataract patients receiving IOLs with a truncated edge. To minimize these effects, efforts to modify the IOL edge have paid off, according to Randall J. Olson, MD.
Povidone-iodine considered best endophthalmitis prophylaxis
April 15th 2003Indianapolis-Preoperative povidone-iodine antisepsis showed the strongest support in the literature for preventing bacterial endophthalmitis in patients undergoing cataract surgery. However, that recommendation was judged to be only "moderately important" to clinical outcome, based on the quality of the available evidence. The review failed to find that any technique was crucial to clinical outcome, said Thomas A. Ciulla, MD.
Automated anterior lamellar keratoplasty offers advantages
April 15th 2003Forli, Italy-Automated anterior lamellar keratoplasty offers a number of advantages over other therapeutic approaches in the treatment of keratoconus, according to Massimo Busin, MD. Importantly, patients experience rapid visual recovery and achieve exceptionally good visual acuity (VA) results.
Monovision LASIK more predictable for myopic patients
April 15th 2003Little Silver, NJ-LASIK monovision is a viable choice for both myopia and hyperopia, but careful patient selection is crucial for best results, particularly among patients with hyperopia, said Daniel B. Goldberg, MD, FACS, Atlantic Laser Center, Little Silver, NJ.
Re-treatment after LASIK is no trivial matter
April 15th 2003Baltimore-Use caution when re-treating a patient who has had refractive surgery, advised Nada S. Jabbur, MD. Just as care should be taken in performing initial LASIK procedures, re-treatments require special care and should not be trivialized, according to Dr. Jabbur.
Antibiotic combats acute bacterial conjunctivitis
April 15th 2003Andover, MA-The antibiotic ISV-401 (InSite Vision, Alameda, CA) in development to treat acute bacterial conjunctivitis has achieved a bacterial eradication rate of 85% by the third day of treatment and 90% by 7 to 9 days, according to a phase II clinical trial.
Patching, atropine offer similar benefits for moderate amblyopia
April 15th 2003Orlando-Children with moderate amblyopia may be successfully treated with patching or atropine drops, regardless of age less than 7 years or depth of amblyopia for the most common causes of amblyopia, according to Michael X. Repka, MD, at the American Academy of Ophthalmology annual meeting.