Susceptibility of S pneumoniae to levofloxacin remains high
July 15th 2006Fort Lauderdale, FL-Results of a nationwide antibiotic susceptibility tracking study demonstrate that despite more than 9 years of widespread systemic and ocular use, levo-floxacin ophthalmic solution 0.5% (Quixin, Santen) has continued to maintain potent activity against Streptococcus pneumoniae, including against multidrug-resistant strains, said Christopher N. Ta, MD.
Study: moxifloxacin yields higher peak levels than gatifloxacin
July 15th 2006Fort Lauderdale, FL-In a comparison of penetration of moxifloxacin HCl ophthalmic solution 0.5% (Vigamox, Alcon Laboratories) and gatifloxacin ophthalmic solution 0.3% (Zymar, Allergan) in a human cornea transplant model, mean peak levels of moxifloxacin were higher than those of gatifloxacin in corneal tissue and the aqueous humor, said Edward Holland, MD.
Intravitreal antibiotic selection may be daunting
July 15th 2006Fort Lauderdale, FL-Intravitreal injection of antibiotics is the primary treatment of endophthalmitis. But not just any antibiotic will do the job-a number of considerations go into choosing an appropriate drug. Travis Meredith, MD, described those clinically relevant factors at the annual meeting of the Association for Research in Vision and Ophthalmology.
ECP at time of phaco effectively lowers IOP
July 15th 2006I have been using endoscopic cyclophotocoagulation (ECP) to treat patients with cataract and medically controlled glaucoma for 5 1/2 years and have found it to be a very useful addition to my armamentarium. The procedure is particularly attractive as an adjunct to small-incision cataract surgery. It takes only about 5 to 10 extra minutes to add ECP to phacoemulsification.
Biomedical science is becoming a roller coaster
July 15th 2006As the years pass, I am amazed at how much ophthalmic practice has changed since my residency, and I think about how things will be even better in the future. Do you remember when glaucoma treatment was pilocarpine, epinephrine, acetazolamide, or surgery? Do you remember when all we could offer someone with macular degeneration and choroidal neovascularization was a low-vision referral? How about 12-mm extracapsular cataract incisions and rigid IOLs without viscoelastics, with each operation taking about 45 minutes of surgical time?
Surgeon incorporates slit lamp exam as part of TASS protocol
July 15th 2006Los Alamitos, CA-Larry Geisse, MD, a surgeon in private practice in Los Alamitos, CA, recently encountered a case of toxic anterior segment syndrome (TASS) that might hold lessons for other clinicians in the treatment of TASS.
Dislocation, decentration concerns for foldable IOLs, survey finds
July 15th 2006San Francisco-The most common complications involving foldable IOLs and requiring explantation showed little change over the past 2 years, according to an annual survey sent to members of the American Society of Cataract and Refractive Surgery (ASCRS) and the European Society of Cataract and Refractive Surgeons (ESCRS).
Ruboxistaurin reduces risk of vision loss in diabetic patients
July 7th 2006Compared with placebo, ruboxistaurin mesylate ( proposed brand name , Arxxant, Eli Lilly and Co.) reduces the risk of sustained moderate vision loss by 41% in patients with moderate-to-severe nonproliferative diabetic retinopathy, according to pooled data from two 3-year phase III trials. Eli Lilly and Co. presented the findings at the American Diabetes Association's annual scientific sessions recently.
(OSI) Eyetech, Pfizer launch phase IV pegaptanib maintenance trial in neovascular AMD
July 7th 2006(OSI) Eyetech Pharmaceuticals Inc. and Pfizer Inc. have initiated a phase IV trial that will study whether use of pegaptanib sodium injection (Macugen) following neovascular age-related macular degeneration (AMD) therapy provides a balance in long-term safety and efficacy. Called LEVEL (EvaLuation of Efficacy and safety in maintaining Visual acuity with sEquential treatment of neovascuLar AMD), the 54-week trial will comprise up to 1,000 patients at 100 sites across the country.
Myopic keratophakia considered alternative for correction of high myopia
July 1st 2006San Francisco-Correction of high myopia with a phakic IOL or by clear lens exchange does pose some risk for patients because these methods are intraocular procedures. To avoid the associated risks of IOL surgery-such as infection, cataract formation in the case of phakic lenses, possible endothelial damage, pupil ovalization, zonular problems, and retinal problems, surgeons might want to consider myopic keratophakia and excimer laser ablation instead, explained Luis Antonio Ruiz, MD.
Graduates of the class of 2006, we salute you!
July 1st 2006Recently it was that time of the year for my medical school's graduation ceremony. Three hours and forty-five minutes of speeches and handing out diplomas, wearing warm academic regalia in an auditorium that could have used more air conditioning-I think you all have been there and know the drill. Deans, vice deans, assistant deans, and department chairmen are accorded the honor of sitting up on the stage, so we get a close-up view of the proceedings.