Transepithelial topography-guided photorefractive keratectomy (TG-PRK) to correct irregular astigmatism after penetrating keratoplasty (PK) is safe and efficacious, according to early study results, said Simon P. Holland, MD, Pacific Laser Eye Care Centre, Vancouver, British Columbia. David Lin, MD, was a study co-author.
It is common that astigmatism is high and irregular after PK, Dr. Holland said.
In this retrospective, nonrandomized consecutive series, researchers focused on contact lens-intolerant eyes that had irregular astigmatism after PK and transepithelial TG-PRK performed with an excimer laser (Schwind Amaris Excimer Laser, Schwind).
Mitomycin 0.02% also was applied. Of 41 eyes treated, 20 had enough data at 1 year for analysis.
Efficacy and safety were analyzed along with preoperative and postoperative uncorrected distance visual acuity (UCDVA), corrected distance visual acuity (CDVA), manifest refraction, topographic cylinder, and the number of Snellen lines gained or lost.
Simon P. Holland, MD
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This article was adapted from a presentation at the 2017 meeting of the American Society of Cataract and Refractive Surgery. Dr. Holland has financial interests with Alcon Laboratories, Allergan, and Schwind.