OCT can detect structural RNFL abnormalities and progression. OCT outperforms measurement of the visual fields (VFs) in detecting progression in early glaucoma. VF progression can be measured even when the VF is normal. In cases of moderate and advanced glaucoma, RNFL progression rate decreases due to a floor effect. It is important to monitor both the RNFL and VF when assessing glaucoma progression, especially in patients with moderate to advanced disease,” Dr. Schuman summarized.