A high prevalence of polymegatism, pleomorphism, and guttata were seen in a study of corneal endothelium changes among an elderly Hispanic population
Reviewed by Jorge Luis Domene Hickman, MD
A study focusing on corneal endothelium changes found that an elderly Hispanic population had a high prevalence of polymegatism, pleomorphism, and guttae, said Jorge Luis Domene Hickman, MD. The results could help to indicate future corneal pathologies that may occur, said Dr. Hickman, Ophthalmology and Visual Sciences Institute, School of Medicine, Monterrey Institute of Technology and Higher Education, Monterrey, Mexico.
A total of 42 patients (22 male, 20 female) and 75 eyes were included in the study. All of the patients were at least 65 years old, with a mean age of 73.9 years. Researchers assessed the central region of the corneal endothelium with specular microscopy (EM-3000, Tomey) to calculate the study’s corneal parameters, including corneal pachymetry.
Study participants were classified in 5-year age ranges, such as 65 to 69 years, 70 to 74 years, etc. All eyes in the study were healthy. Exclusion criteria included previous ocular surgery, glaucoma, and photocoagulation, Dr. Hickman said.
Polymegatism was considered when the coefficient of variation of the cell area was higher than 40%. Pleomorphism was considered when fewer than 50% of the cells were six-sided.
Jorge Luis Domene Hickman, MD
E: [email protected]
This article was adapted from Dr. Hickman’s poster at the 2018 meeting of the American Academy of Ophthalmology. Dr. Hickman has no related disclosures.