A team of seven leading ophthalmologists has been assembled to evaluate the accommodative properties of a proprietary material (Collamer, STAAR Surgical) used in the company's accommodating IOLs, it was announced in a prepared statement.
Intracameral injection of triamcinolone is very useful for "staining" vitreous that has prolapsed into the anterior segment to enable vitrectomy. Safety is favorable, but there are some issues to consider.
Alcon Inc. has executed a new agreement and broadened an existing agreement with two different companies to expand its products under development.
Advanced Medical Optics (AMO) voluntarily recalled a single lot of its ophthalmic viscosurgical device ([OVD] Healon D) after physicians noticed inflammation at some patients' 1-day postoperative visit.
1-year results from the HORIZON open-label extension study of ranibizumab (Lucentis, Genentech) for the treatment of exudative age-related macular degeneration show that treatment beyond 2 years relatively is safe and well tolerated, but previously treated patients who received ranibizumab monthly for 2 years may be susceptible to loss of vision with less-frequent dosing during the third year of treatment.
A new intravitreal insert (Iluvien, Alimera Sciences) currently in clinical trials manages a slow, long-term release of corticosteroid into the vitreous chamber. Preliminary results show the device to be very promising and possibly more favorable than other similar devices used for the treatment of diabetic macular edema.
In a dose-ranging phase IIb study, microplasmin 125 micrograms (ThromboGenics) was safe and demonstrated significant efficacy compared with placebo for inducing posterior vitreous detachment in eyes with macular holes or macular edema related to vitreomacular traction. Pivotal phase III trials are being planned.
A prismatic IOL (P-Flex, Rayner) is giving hope to patients with advanced age-related macular degeneration because of its novel design. A Fresnel prism in the IOL reflects images onto healthy retinas in patients with small macular lesions. No scotoma or diplopia has resulted from implantation of this IOL in two patients.
Neovascular age-related macular degeneration patients see significant gains in visual acuity when treated with vascular endothelial growth factor therapy
Visual acuity gains occurring in a 12-week, fixed-dose period were maintained throughout the 52-week trial of a novel agent (VEGF Trap-Eye, Regeneron Pharmaceuticals) for neovascular age-related macular degeneration. During the 9-month, as-needed dosing phase, the mean number of injections for all patients was two, and gains in visual acuity of up to nine letters were reported.
Adjuvant use of bromfenac ophthalmic solution 0.09% (Xibrom, ISTA Pharmaceuticals) with ranibizumab (Lucentis, Genentech) reduced the reduced the number of ranibizumab injections needed to control choroidal neovascularization secondary to age-related macular degeneration. Use of the two drugs together resulted in better visual acuity outcomes than those achieved with ranibizumab alone.