Repeat-selective laser trabeculoplasty (SLT) administered during the LIGHT Trial lowered intraocular pressure (IOP) in eyes with IOP increases during 1.5 years after the initial SLT application. The decrease lasted longer than the initial lowering.
Dr. Gazzard reported that the mean IOP was higher before the initial SLT compared with the repeat-SLT (24.5 versis 21.0 mm Hg, p < 0.001).
“We did not allow the patients to return to the baseline IOPs before we re-intervened, to mirror normal clinical practice,” he pointed out.
At that important two-month time point, the absolute IOP reduction was greater after the initial SLT, that is 5.3 versus 4.6 mm Hg (p = 0.02).
Dr. Gazzard also explained that if the two-month IOP adjusted for the starting IOP immediately before laser treatment was used, there was a greater adjusted effect after the repeat-SLT.
“The adjusted difference between the primary laser and the repeat laser showed that the latter seemed to be producing a greater proportional effect,” he said.