By Vanessa Caceres; Reviewed by Robert Ritch, MD
A supplement with antioxidant and mitoprotective properties has shown to reverse mitochondrial dysfunction and may be neuroprotective for glaucoma, according to a recent study.
Robert Ritch, MD, the Steven and Shelley Einhorn Distinguished Chair, professor of ophthalmology, New York Eye and Ear Infirmary of Mount Sinai, New York, outlined the results of the study that focused on whether a combination of over-the-counter supplements with antioxidant and mitoprotective properties could reverse mitochondrial dysfunction by reducing mitochondrial flavoprotein fluorescence compared with placebo.
A total of 14 patients (n = 28 eyes) were divided into either a placebo group or a group that received a combination of curcumin, Ginkgo biloba extract, citicoline, coenzyme-Q10 (ubiquinol, Cognizin), N-acetyl-cysteine, alpha-lipoic acid, grapeseed extract, and green tea extract. All of the aforementioned are part of a supplement called Glauco-Health (Guardion Health Sciences).
Dr. Ritch and co-investigators from Ramathibodi Hospital, Mahidol University, Bangkok, Thailand; and Columbia University, New York, conducted the study as part of an Investigational New Drug application from the FDA.